[Different types of blood lipoproteins in psoriasis patients. 1. The relationship of dyslipoproteinemias due to disordered cholesterol transport and the course of psoriasis].

Comparison of the course of psoriasis in patients with hypo- and hyperalphacholesterolemia, hypo- and hyperbetacholesterolemia (Type IIA hyperlipoproteinemia) with that in the patients without identified lipid metabolism disturbances has been carried out. Blood lipoproteins were typed in the progressive stage of psoriasis. In hypoalphacholesterolemia patients the period of the psoriatic process stabilization was prolonged.

[Effect of caffeine and glycerin on the Ca transport system of sarcoplasmic reticulum fragments from frog skeletal muscles].

Parameters of the Ca2+-ion transport system by a fragmented sarcoplasmic reticulum isolated from phasic and tonic frog skeletal muscles were investigated under the action of caffeine or caffeine in combination with glycerol. No changes were observed in the Ca-transport system of a light fraction of the sarcoplasmic reticulum under the influence of caffeine and caffeine-glycerol combination. Caffeine reduced the value of Ca/ATP and enhanced the outflux of Ca2+-ions from membrane fragments of the caffeine-sensitive sarcoplasmic reticulum fraction of both the muscles; the combined effect of caffeine and glycerol was analogous to the action of caffeine applied alone.

[Causative factor of Ca2+ transport reduction by sarcoplasmic reticulum fragments under the action of acetylcholine].

The uncoupling of Ca2+ uptake and ATP hydrolysis by acetylcholine (ACh) and choline has been demonstrated on fragmented sarcoplasmic reticulum (FSR) isolated from femoral muscles of Rana ridibunda. The uncoupling depends on the content of oxalate in the incubation medium. An increase in the Ca/ATP ratio caused by serum albumin observed at low oxalate concentrations is indicative of participation of free fatty acids in the uncoupling effect of ACh and choline.