Competitive Adsorption of a Monoclonal Antibody and Nonionic Surfactant at the PDMS/Water Interface.

Interfacial adsorption of monoclonal antibodies (mAbs) can cause structural deformation and induce undesired aggregation and precipitation. Nonionic surfactants are often added to reduce interfacial adsorption of mAbs which may occur during manufacturing, storage, and/or administration. As mAbs are commonly manufactured into ready-to-use syringes coated with silicone oil to improve lubrication, it is important to understand how an mAb, nonionic surfactant, and silicone oil interact at the oil/water interface.

Self-assembly followed by radical polymerization of ionic liquid for interfacial engineering of black phosphorus nanosheets: Enhancing flame retardancy, toxic gas suppression and mechanical performance of polyurethane.

As one of emerging layered nanomaterials, the potential of black phosphorous nanosheets (BP) for fabricating high performance polymer composites was seriously confined by incompatible interface. Herein, interfacial engineering between BP nanosheets and polyurethane (PU) matrix was rationally designed, where employing polymerized ionic liquid as linking bridge between robust BP nanosheets and soft TPU. The ionic liquid (IL) was firstly confined onto the surface of BP nanosheets with the combination of electrostatic-driving self-assembly process and in situ radical polymerization was then performed.