Publications by authors named "Zeynep Ural"
Scabies, caused by the Sarcoptes scabiei var hominis mite burrowing into the skin, is a highly contagious disease characterized by intense nocturnal itching. Its global impact is considerable, affecting more than 200 million individuals annually and posing significant challenges to healthcare systems worldwide. Transmission occurs primarily through direct skin-to-skin contact, contributing to its widespread prevalence and emergence as a substantial public health concern affecting large populations.
View Article and Find Full Text PDFKidney failure patients on chronic hemodialysis are at risk for cardiovascular complications. Dry weight (DW), one of the dialysis parameters, should be optimized to reduce the complications caused by high blood pressure. By definition, DW is the lowest weight at which patients are clinically euvolemic, not hypotensive or hypertensive after dialysis, and do not require antihypertensives.
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- The study aimed to compare clinical outcomes between peritoneal dialysis (PD) patients who had COVID-19 and a control group of PD patients without COVID-19, as there was limited data on this topic.
- The research involved 223 patients (113 with COVID-19 and 110 controls) and found that while general characteristics were similar, the COVID-19 group had lower serum albumin and hemoglobin levels and more complications like respiratory symptoms and rehospitalization on day 28.
- Over a 90-day period, mortality rates were low (1 death in the COVID-19 group), and although some health issues persisted for patients who had COVID-19, overall mortality did not significantly differ from the control group.
Introduction: We aimed to study the characteristics of peritoneal dialysis (PD) patients with coronavirus disease-19 (COVID-19), determine the short-term mortality and other medical complications, and delineate the factors associated with COVID-19 outcome.
Methods: In this multicenter national study, we included PD patients with confirmed COVID-19 from 27 centers. The baseline demographic, clinical, laboratory, and radiological data and outcomes at the end of the first month were recorded.
Article Synopsis
- Idiopathic focal segmental glomerulosclerosis (FSGS) is a significant cause of kidney failure in adults and often recurs after kidney transplants, with limited treatment options for those who don't respond to standard therapies.
- A case study of a 44-year-old man showed that after multiple failed treatments for recurrent FSGS post-transplant, he experienced an unexpected partial remission after starting ofatumumab, which is a newer treatment.
- The observation suggests that ofatumumab might be a viable alternative for patients who are resistant to existing treatments like plasmapheresis and rituximab.
Background: In this study, we evaluated 3-month clinical outcomes of kidney transplant recipients (KTR) recovering from COVID-19 and compared them with a control group.
Method: The primary endpoint was death in the third month. Secondary endpoints were ongoing respiratory symptoms, need for home oxygen therapy, rehospitalization for any reason, lower respiratory tract infection, urinary tract infection, biopsy-proven acute rejection, venous/arterial thromboembolic event, cytomegalovirus (CMV) infection/disease and BK viruria/viremia at 3 months.
Introduction: Hemodialysis (HD) patients have increased risk for short-term adverse outcomes of COVID-19. However, complications and survival at the post-COVID-19 period have not been published extensively.
Methods: We conducted a national, multicenter observational study that included adult maintenance HD patients recovered from confirmed COVID-19.
Objective: To determine the prevalence of sarcopenia in patients with chronic kidney disease (CKD), investigate the relationship of the serum myostatin level with sarcopenia and inflammatory markers.
Methods: The study was conducted with four patient groups: renal transplantation (TX), stage 3-5 non-dialysis-dependent CKD (NDD-CKD), hemodialysis (HD), and peritoneal dialysis (PD). Laboratory parameters, serum myostatin, C-reactive protein, and interleukin-6 levels were studied.
DNA isolation by galactoacrylate-based nano-poly(HEMA-co-Gal-OPA) nanopolymers.
J Biomater Sci Polym Ed
October 2017
Isolation of DNA is one of the important processes for biotechnological applications such as investigation of DNA structures and functions, recombinant DNA preparations, identification of genetic factors and diagnosis and treatment of genetic disorders. The aim of this study was to synthesis and characterizes the galactoacrylate based nanopolymers with high surface area and to investigate the usability of these synthesized nanopolymers for DNA isolation studies. Nanopolymers were synthesized by the surfactant free emulsion polymerization technique by using the monomers of 2-hydroxyl ethylmethacrylate and 6-O-(2-hydroxy-3-acryloyloxypropyl)-1,2:3,4-di-O-isopropylidene-α-D-galactopyranose.
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