FourierNet: Shape-Preserving Network for Henle's Fiber Layer Segmentation in Optical Coherence Tomography Images.

Henle's fiber layer (HFL), a retinal layer located in the outer retina between the outer nuclear and outer plexiform layers (ONL and OPL, respectively), is composed of uniformly linear photoreceptor axons and Müller cell processes. However, in the standard optical coherence tomography (OCT) imaging, this layer is usually included in the ONL since it is difficult to perceive HFL contours on OCT images. Due to its variable reflectivity under an imaging beam, delineating the HFL contours necessitates directional OCT, which requires additional imaging.

HENLE FIBER LAYER MAPPING WITH DIRECTIONAL OPTICAL COHERENCE TOMOGRAPHY.

Purpose: To perform a macular volumetric and topographic analysis of Henle fiber layer (HFL) from retinal scans acquired by directional optical coherence tomography.

Methods: Thirty healthy eyes of 17 subjects were imaged using the Heidelberg spectral-domain optical coherence tomography (Spectralis, Heidelberg Engineering, Heidelberg, Germany) with varied horizontal and vertical pupil entry. Manual segmentation of HFL was performed from retinal sections of horizontally and vertically tilted optical coherence tomography images acquired within macular 20 × 20° area.

3D printed personalized magnetic micromachines from patient blood-derived biomaterials.

While recent wireless micromachines have shown increasing potential for medical use, their potential safety risks concerning biocompatibility need to be mitigated. They are typically constructed from materials that are not intrinsically compatible with physiological environments. Here, we propose a personalized approach by using patient blood–derivable biomaterials as the main construction fabric of wireless medical micromachines to alleviate safety risks from biocompatibility.