Is Human Oxoguanine Glycosylase 1 Genetic Variant Successful Even on Oral Squamous Cell Carcinoma?

Background: Oral squamous cell carcinoma (OSCC) is one of the most widespread cancer types that arise from different sites of oral cavity and has a 5-year survival rate. This study is aimed at investigating the human oxoguanine glycosylase 1 (hOGG1)-Ser326Cys and APE-Asp148Glu polymorphisms of DNA repair genes in OSCC.

Materials And Methods: We investigated the hOGG1-Ser326Cys and APE-Asp148Glu polymorphisms of DNA repair genes in the oral cavity.

The prevalence of oral mucosal lesions in children:a single center study.

Purpose: Studies regarding oral health are mainly conducted on adult population and there is a lack of epidemiologic data on the oral health of children. The purpose of this study was to evaluate the prevalence and distribution of oral lesions in Turkish children.

Materials And Methods: A cross-sectional survey was carried out on total of 1041 Turkish children attended by the outpatient Oral Medicine and Surgery Department of İstanbul University.

Burning mouth syndrome.

Burning mouth syndrome (BMS) is characterized by oral burning or similar pain in the absence of detectable oral mucosa changes. This condition is more common among middle-aged and elderly women. Although various local, systemic, and psychological factors are considered to be possible causes of BMS, it is still a challenge in the field of oral medicine.