Publications by authors named "Zeynel Karcıoglu"
Article Synopsis
- The report discusses a case of a 9-year-old boy with left-sided eyelid ptosis, which is an unusual symptom not linked to common causes like infections.
- MRI results showed pansinusitis and otitis media that affected the muscle responsible for lifting the upper eyelid, providing a specific diagnosis.
- This case highlights the importance of thorough imaging to identify underlying issues in cases of ptosis that don't fit typical presentations.
Article Synopsis
- Macular corneal dystrophy is a genetic condition characterized by abnormal proteoglycan synthesis, leading to progressive vision loss due to corneal opacity.
- Advanced imaging techniques, like in vivo confocal microscopy and anterior segment ocular coherence tomography, improve understanding of the condition's impact on corneal structure without invasive procedures.
- While traditional treatments like penetrating keratoplasty are effective, new approaches such as gene-targeting therapies and enzyme replacement therapies are being explored to address the underlying causes and improve visual outcomes.
Article Synopsis
- Hepatic pathology can have hidden connections to eye diseases, impacting areas around the eyes like the eyelids and orbits.
- The review covers different eye-related issues linked to liver disorders, including jaundice, hepatitis effects, and specific conditions like cirrhosis-related eyelid changes.
- It also discusses more complex conditions such as Wilson disease and Alagille syndrome, along with the implications of liver transplantation on eye health.
Purpose: The aim of this study was to identify the risk factors that are predictive of poor outcomes in penetrating globe trauma.
Patients And Methods: This retrospective case series evaluated 103 eyes that had been surgically treated for an open-globe injury from 2007 to 2010 at the eye clinic of the University of Virginia. A total of 64 eyes with complete medical records and at least 6 months of follow-up were included in the study.
Congenital intrascleral cysts are rare. They are mostly located at the limbus with corneal involvement. We report a case of a 30-month-old boy with a bulber conjunctival cyst noticed at birth.
View Article and Find Full Text PDFKlebsiella pneumoniae endophthalmitis secondary to liver abscess presenting as acute iridocyclitis.
Ophthalmic Surg Lasers Imaging
November 2009
A 51-year-old man presented with acute iridocyclitis with no evidence of vitritis on B-scan that progressed to endogenous endophthalmitis. Systemic work-up revealed a large liver abscess. Urine, blood, liver abscess, and vitreous aspirate cultures all grew Klebsiella pneumoniae.
View Article and Find Full Text PDFIntraocular pressure change has been found concurrent with many orbital pathologies, particularly those involving proptosis. The objective of this review is to offer an inclusive classification of orbital disease-related intraocular pressure change, not only for oculoplastics and glaucoma specialists, but also for general ophthalmologists. Various orbital conditions associated with increased intraocular pressure and glaucoma are comprehensively summarized, and pathophysiology, clinical manifestations, and treatment options of these diseases are discussed.
View Article and Find Full Text PDFArticle Synopsis
- The case involves a 20-month-old girl diagnosed with unilateral retinoblastoma, leading to the enucleation of her right eye after identifying the cancer through cytopathology.
- Post-surgery, a CT scan revealed a questionable area in the remaining optic nerve, which necessitated further exploration since the enucleated eye was lost.
- Histopathological analysis of the optic nerve stump revealed no signs of retinoblastoma, complicating the treatment process as proper staging and planning rely heavily on histopathological findings.
A 48-year-old woman with a history of chronic intranasal cocaine abuse presented with unilateral proptosis associated with severe visual loss from optic neuropathy in the right eye. Imaging showed extensive bone and soft tissue destruction in the paranasal region and an orbital mass. Initial biopsies suggested a low-grade neoplasm.
View Article and Find Full Text PDFPurpose: To report the development of unilateral, diffuse hyperostosis of orbital bones in 3 postexenteration patients.
Methods: Three advanced cases of periorbital and orbital malignancies are presented, and their clinical, radiologic, and histopathologic features are reviewed.
Results: Postexenteration CT showed thickened orbital walls in all 3 cases.
Article Synopsis
- Subgaleal hemorrhage (SGH) can occur after various types of head trauma in children, leading to serious complications.
- In a reported case, a child with SGH experienced bilateral orbital hemorrhages and loss of vision, requiring surgery.
- The article also includes a review of existing literature on SGH and its potential complications.
Article Synopsis
- Degas suffered from an eye disease that began in 1870, leading to progressive central vision loss and light sensitivity, impacting his ability to paint outdoors, especially in bright conditions.
- The analysis included Degas' paintings, personal letters, and family papers, revealing a potential hereditary retinal degeneration shared with his cousin Estelle Musson, who also experienced visual loss.
- Despite these challenges, Degas continued to create iconic art and became one of the most celebrated painters in history.
Conjunctival biopsy of anophthalmic socket in sarcoidosis.
Ophthalmic Plast Reconstr Surg
March 2005
Article Synopsis
- A 22-year-old black female with a history of eye injuries presented with uveitis and nodules in her left eye, and her right eye had been enucleated.
- A biopsy of these nodules did not show the expected granulomatous inflammation, but a random biopsy from her anophthalmic socket revealed noncaseating granulomas, confirming a diagnosis of sarcoidosis.
- This case is significant as it is the first known instance where sarcoidosis was diagnosed through a conjunctival biopsy from an anophthalmic socket, highlighting this method as a reliable, economical diagnostic tool.
Russell-Silver syndrome (RSS) primarily includes intrauterine growth retardation, postnatal growth failure, body asymmetry, and craniofacial disproportion. Four types of malignancies have been reported in patients with RSS: craniopharyngioma, testicular seminoma, hepatocellular carcinoma, and Wilms tumor.
View Article and Find Full Text PDFObjective: To examine the expression of molecules targeted by imatinib mesylate (STI571;Gleevec) and epidermal growth factor receptor (EGFR) inhibitors in orbital lymphangiomas.
Design: Retrospective observational case series.
Participants: Six patients with orbital lymphangioma treated at four institutions between March 2000 and December 2002.
Article Synopsis
- Rhabdomyosarcoma (RMS) is a rare but significant eye tumor that poses diagnostic and management challenges for ocular oncologists, often appearing in the first decade of life.
- Commonly found in the superior nasal quadrant of the orbit, RMS can mimic other lesions, with its effects varying based on tumor location and growth rate.
- Advances in chemotherapy and radiotherapy have improved survival rates, but posttreatment complications like secondary malignancies and visual dysfunction present new challenges for long-term care.
Objective: To study the histopathological changes in the optic nerve following posterior insertion of a glaucoma drainage device.
Methods: The Ahmed glaucoma valve (AGV) (model no. S-3) was inserted 10 to 12 mm behind the limbus in the superotemporal quadrant of the rabbit eye.
Orbital xanthogranuloma: clinical and morphologic features in eight patients.
Ophthalmic Plast Reconstr Surg
September 2003
Purpose: To describe the clinical and morphologic features of patients with orbital xanthogranuloma (XG) with or without Erdheim-Chester disease (E-Cd).
Methods: Retrospective, noncomparative case series. A review of 8 consecutive histopathologically proven cases of orbital XG from 3 medical centers.
Article Synopsis
- The study aimed to investigate the use of fine needle aspiration biopsy (FNAB) for diagnosing retinoblastoma (RB) and its related factors and complications.
- A survey was conducted among 12 ocular oncology clinics, revealing that only 8 biopsies were performed in a total of 3,651 RB patients over the last 15 years.
- Findings indicated that FNAB is rarely needed for RB diagnosis, as most cases can be effectively diagnosed by ocular oncologists without the need for invasive procedures.