Publications by authors named "Zeynab Danesh"

Keratoconus (KC) is characterized by the predominant primary ectatic disease, affecting the cornea, necessitating corneal transplants in some cases. While some loci associated with KC risk have been identified, the understanding of the disease remains limited. Superoxide dismutase (SOD) enzymes play a crucial role in countering the reactive oxygen species and providing protection against oxidative stress (OS).

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Purpose: To assess corneal stability and corrected distance visual acuity (CDVA) 3, 6, and 12 months following corneal cross-linking (CXL) using the ABCD keratoconus staging system.

Methods: This prospective longitudinal study included 31 eyes with keratoconus receiving CXL based on the standard Dresden protocol. CDVA, refraction, and Scheimpflug tomography with the Pentacam HR (Oculus Optikgeräte GmbH) were evaluated before and after surgery.

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Purpose: To compare the biomechanically-corrected intraocular pressure (bIOP) measured by the Corvis ST (Oculus, Wetzlar, Germany) with IOP measurements made by other commonly used tonometers; and to test the correlations between IOP measures and central corneal thickness.

Methods: One randomly-selected eye from each of 94 healthy subjects was assessed. The bIOP was determined by the CorVis ST and compared with the IOP measurements made by standard Goldmann Applanation Tonometer (GAT: Haag-Streit AG, Bern, Switzerland), the Icare (Icare Finland Oy, Vantaa, Finland), and the Ocular Response Analyzer (ORA-IOPcc: Reichert, New York, USA).

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Purpose: To compare the long-term changes in corneal biomechanics, topography, and tomography before and 4 years after corneal cross-linking (CXL) with the Dresden protocol and correlate these changes with visual acuity.

Methods: In this longitudinal study, 18 eyes of 18 patients with progressive keratoconus who were treated with CXL were included. All patients received a standard ophthalmological examination and were examined by Placido disc-based topography, Scheimpflug tomography, and biomechanical assessments with the Corvis ST (OCULUS Optikgeräte GmbH, Wetzlar, Germany) and Ocular Response Analyzer (ORA; Reichert Ophthalmic Instruments, Buffalo, NY) before and 4 years after CXL.

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Purpose: To assess the diagnostic capability of corneal shape and biomechanical parameters for distinguishing normal eyes from frank keratoconus (KCN).

Methods: This is a retrospective analysis of eyes of 137 control subjects and 145 patients with KCN, with one of their eyes randomly selected as the study eye. Corneal biomechanical parameters were assessed using the Corvis ST (Oculus Optikgeräte GmbH) and Oculus Response Analyzer (Reichert Ophthalmic Instruments).

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