The overestimated risks for imported waste paper: Based on grey interval multi-criteria decision making under uncertainties.

China has prohibited the imported waste paper (IWP) from 2021 due to environmental burdens, its reasonability was doubtful owing to lacking a comprehensive evaluation. Previous studies just assessed the potential risks caused by pollutants from the upstream processes, ignoring the actual risks from the actual production processes, especially the generated toxic pollutants (heavy metals, PCDD/Fs, PAEs and DL-PCBs). Herein, ITOPSIS-IVIKOR-GRA incorporating distance and correlation by combining grey distance, grey group utility and individual regret, was developed to prioritize the risks of four typical recycled paper production by taking potential/actual health and ecological risks as criteria.

PXR Activation Relieves Deoxynivalenol-Induced Liver Oxidative Stress Via Malat1 LncRNA mA Demethylation.

Deoxynivalenol (DON) is a prevalent toxin causing severe liver damage through hepatocellular oxidative stress. However, the underlying mechanisms and effective therapeutic approaches remain unknown. Here, the unique role of the xenobiotic metabolism factor pregnane X receptor (PXR) in mediating DON-induced hepatocellular oxidative stress is investigated.

Hole Matrix Mapping Model for Partitioned Sitting Surface Based on Human Body Pressure Distribution Matrix.

(1) Objective: The objective of this study was to experimentally obtain the ideal pressure distribution model of buttock and thigh support for office workers in forward-leaning and upright sitting postures, reproduce the support provided by mesh materials with elastic materials, and propose an effective seat design scheme to improve the comfort of office workers. (2) Method: Based on the seven most popular mesh chairs on the market, pressure distribution experiments, and the fuzzy clustering algorithm, the relatively ideal body pressure distribution matrices were generated for office workers under two common sitting postures, and the corresponding partitioned sitting support surfaces were obtained. A prototype chair was created and validated by combining the ergonomics node coordinates and the physical properties of the materials.

Efficiency of sulfamethoxazole removal from wastewater using aerobic granular sludge: influence of environmental factors.

The effects of adsorption, sulfamethoxazole (SMX) content, chemical oxygen demand (COD), and dissolved oxygen (DO) are recognized to be crucial for SMX removal in the aerobic granular sludge (AGS) system. Therefore, we investigated the impact of adsorption and these three different environmental factors on the SMX removal loading rate and removal efficiency of an AGS system, and determined the differences in microbial community composition under different environmental conditions. Adsorption was not the main SMX removal mechanism, as it only accounted for 5% of the total removal.

Effects of sulfamethoxazole on aerobic sludge granulation process.

Aims: Our purpose was to clarify the effect of sulfamethoxazole (SMX) on the start-up period, particle formation, and treatment efficiency of an aerobic granular sludge system.

Methods And Results: We compared an R1 granular sequencing batch reactor (GSBR) started with 5 μg L SMX and an R2 GSBR started without SMX, as a control, to investigate the impact of a trace amount of SMX (5 μg L ) on aerobic granular sludge (AGS) characteristics and the removal of conventional contaminants. AGS granulation in the R1 system was not inhibited by SMX, but the granule particle size was smaller than that in the R2 system.

A Systematic Review of Tissue Engineering Scaffold in Tendon Bone Healing .

Tendon-bone healing is an important factor in determining the success of ligament reconstruction. With the development of biomaterials science, the tissue engineering scaffold plays an extremely important role in tendon-bone healing and bone tissue engineering. Electronic databases (PubMed, Embase, and the Web of Science) were systematically searched for relevant and qualitative studies published from 1 January 1990 to 31 December 2019.

Endoplasmic reticulum stress-mediated autophagy contributes to 5-ethylamino-9-diethylaminobenzo[a]phenoselenazinium-mediated photodynamic therapy via the PERK-eIF2α pathway.

Introduction: 5-ethylamino-9-diethylaminobenzo[a]phenoselenazinium (EtNBSe) is a novel synthetic bipolar photosensitizer with many promising applications. This study investigated the impact of EtNBSe-mediated photodynamic therapy (EtNBSe-PDT) on the autophagy and endoplasmic reticulum (ER) stress of squamous carcinoma cells (A-431 cells), as well as the related molecular mechanisms.

Methods: The potency of EtNBSe-PDT against squamous cell carcinoma was evaluated in BALB/c nude mice.

Human mesenchymal-stem-cells-derived exosomes are important in enhancing porcine islet resistance to hypoxia.

Background: Hypoxia-induced damage is one of the key factors associated with islet graft dysfunction. Mesenchymal stem cells (MSCs) could be used to enhance the therapeutic effect of islet transplantation due to their paracrine potential such as exosomes. In this study, we investigated whether exosomes from human umbilical cord-derived MSC-conditioned medium (hu-MSC-CM) could increase the survival and function of neonatal porcine islet cell clusters (NICCs) exposed to hypoxia.