Prognostic biomarker IL17A correlated with immune infiltrates in head and neck cancer.

Background: The underlying functions and mechanisms of the Th17 pathway in Head and neck squamous cell carcinoma (HNSCC) progression and tumor immunology are still unclear. We investigated the correlation between IL17A expression and certain clinical parameters, tumor-infiltrating immune cells (TIICs) in TCGA HNSCC samples.

Methods: HNSCC files from the TCGA database were analyzed to obtain data on immune system infiltrates, gene expression, and related clinical information.

Benign paroxysmal positional vertigo and serum transthyretin in Chinese older adults.

Background And Objectives: Poor nutritional status is associated with benign paroxysmal positional vertigo (BPPV). Transthyretin (TTR) is a more sensitive marker than is albumin for nutritional status assessment. This study was conducted to confirm an association between serum transthyretin levels and BPPV.

miR-339-5p Inhibits Autophagy to Reduce the Resistance of Laryngeal Carcinoma on Cisplatin via Targeting TAK1.

Laryngeal carcinoma is a malignant disease with high morbidity and mortality. Several studies have indicated that miRNA dysfunction involves in the development of laryngeal carcinoma. In this study, the connection of miR-339-5p and laryngeal carcinoma was investigated, and qRT-PCR, CCK-8, and flow cytometry assay were used to observe the function of miR-339-5p on laryngeal carcinoma.

[Deep neck infection: clinical analyses of 95 cases].

Objective: To review the recent diagnosis and treatment experience with deep neck infection and emphasize the importance of radiologic evaluation, microbiology and appropriate treatment selection in these patients.

Methods: A respective review was conducted in 95 cases who were diagnosed as having deep neck from Jan. 2006 to March 2015.

[Clinal analysis of 202 nasal bone fractures cases].

Objective: To evaluate the age, sex, etiology, diagnosis and treatment time of nasal bone fractures.

Method: Clinical data of 202 cases with nasal bone fractures treated in the hospital were retrospectively analysed.

Result: A total of 202 cases,163 men (80.