Tmed10 deficiency results in impaired exocrine pancreatic differentiation in zebrafish larvae.

Transmembrane p24 trafficking protein 10 (TMED10) is a conserved vesicle trafficking protein. It is dysregulated in Alzheimer disease and plays a pivotal role in the pathogenesis of Alzheimer disease. In addition to the brain, TMED10 is highly expressed in the exocrine pancreas; however, its biological functions and underlying mechanisms remain largely unknown.

Adaptive neural network projection analytical fault-tolerant control of underwater salvage robot with event trigger.

Introduction: To solve the problem of control failure caused by system failure of deep-water salvage equipment under severe sea conditions, an event-triggered fault-tolerant control method (PEFC) based on proportional logarithmic projection analysis is proposed innovatively.

Methods: First, taking the claw-type underwater salvage robot as the research object, amore universal thruster fault model was established to describe the fault state of equipment failure, interruption, stuck, and poor contact. Second, the controller was designed by the proportional logarithmic projection analytical method.