Publications by authors named "Zeshan Chisty"

Article Synopsis
  • The study focused on the immune response to SARS-CoV-2 infection and COVID-19 vaccination among 37 nursing home residents, highlighting the importance of this high-risk group.
  • Researchers measured antibody levels and memory B cell responses to evaluate the impact of vaccinations and infections over time.
  • Results indicated that while vaccination boosts the immune response, there is a decline in antibody levels over time, and individuals who get infected after vaccination show lower antibody levels compared to those who remain uninfected.
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Article Synopsis
  • In August 2022, a nurse in Florida contracted monkeypox from a patient while on the job, marking the first reported case in the U.S. related to occupational exposure.
  • Cases of monkeypox among healthcare personnel have been uncommon during the 2022 multinational outbreak.
  • The report emphasizes the need for preventive measures to protect healthcare workers from acquiring monkeypox in the workplace.
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Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can spread rapidly within skilled nursing facilities. After identification of a case of Covid-19 in a skilled nursing facility, we assessed transmission and evaluated the adequacy of symptom-based screening to identify infections in residents.

Methods: We conducted two serial point-prevalence surveys, 1 week apart, in which assenting residents of the facility underwent nasopharyngeal and oropharyngeal testing for SARS-CoV-2, including real-time reverse-transcriptase polymerase chain reaction (rRT-PCR), viral culture, and sequencing.

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Article Synopsis
  • Older adults face a higher risk of severe COVID-19 outcomes due to age and health conditions, as illustrated by an outbreak in a King County skilled nursing facility that began on February 28, 2020.
  • A health care worker at a second facility (Facility A) tested positive for SARS-CoV-2 after working while showing symptoms, leading to the identification of multiple symptomatic residents by March 6.
  • Testing at Facility A revealed that around 30% of residents tested positive for COVID-19, with many being asymptomatic, highlighting the ineffectiveness of symptom-based screening and the need for proactive measures to prevent virus introduction.
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