Study on the Characteristics of Traditional Chinese Medicine Syndromes in Patients with Erosive Gastritis Based on Metabolomics.

According to traditional Chinese medicine theory, tongue coatings reflect changes in the body. The goal of this study was to identify a metabolite or a set of metabolites capable of classifying characteristics of traditional Chinese medicine syndromes in erosive gastritis. In this study, we collected tongue coatings of patients with erosive gastritis with damp-heat syndrome (DHS), liver depression and qi stagnation syndrome (LDQSS), and healthy volunteers.

Widely tunable NCPM-KTA OPO based on non-collinear phase-matching in a four-mirror ring cavity.

Based on non-collinear phase-matching (PM), a new method for widely tunable wavelength was proposed and demonstrated in a four-mirror ring cavity of non-critical phase-matching (NCPM) KTiOAsO (KTA) optical parametric oscillator (OPO). Wavelength tuning range of 141 nm from 1535.56 nm to 1676.

Shengxian decoction protects against chronic heart failure in a rat model via energy regulation mechanisms.

Background: Chronic heart failure (CHF) is actually a disease caused by an imbalanced energy metabolism between myocardial energy demand and supply, ultimately resulting in abnormal myocardial cell structure and function. Energy metabolism imbalance plays an important role in the pathological process of chronic heart failure (CHF). Improving myocardial energy metabolism is a new strategy for the treatment of CHF.

The therapeutic effect of Huazhuojiedu decoction on precancerous lesions in a gastric cancer model via the regulation of lnc 517368.

Ethnopharmacological Relevance: Huazhuojiedu decoction, a Chinese herbal preparation, has been proven to be clinically effective in treating precancerous lesions in gastric cancer (PLGC). This formula is optimized from a classic formula called "Ganluxiaodu Dan." Although some experiments have shown that Huazhuojiedu decoction is effective against PLGC, the mechanism remains unclear.

Determination of the protective effects of Hua-Zhuo-Jie-Du in chronic atrophic gastritis by regulating intestinal microbiota and metabolites: combination of liquid chromatograph mass spectrometer metabolic profiling and 16S rRNA gene sequencing.

Background: Hua-Zhuo-Jie-Du (HZJD), a Chinese herbal prescription consisting of 11 herbs, is commonly used in China to treat chronic atrophic gastritis (CAG). We aimed to determine the effect of HZJD on the microbiome-associated metabolic changes in CAG rats.

Methods: The CAG rat models were induced by 1-methyl-3-nitro-1-nitrosoguanidine (MNNG) combined with irregular fasting and 2% sodium salicylate, which was intragastrically administrated in fasted animals for 24 weeks.

Integrating Network Pharmacology and Experimental Validation to Investigate the Mechanisms of Huazhuojiedu Decoction to Treat Chronic Atrophic Gastritis.

Background: Chronic atrophic gastritis (CAG) is an important stage in the normal gastric mucosa's transformation into gastric cancer. Huazhuojiedu decoction (HZJD), a Chinese herbal preparation, has proven clinically effective to treat CAG. However, few studies have explored the mechanism of HZJD in CAG treatment.

Association between gastroesophageal reflux disease and depression disorder: A protocol for systematic review and meta-analysis.

Background: This study will systematically synthesize the evidence on the potential association between gastroesophageal reflux disease (GERD) and depression disorder (DD).

Methods: We will search the following electronic bibliographic databases: PubMed/MEDLINE, Embase, Cochrane Library, Web of Science, the Chinese Bio Medical Literature Database, China National Knowledge Infrastructure (CNKI), the China Science and Technology Journal database (VIP) and Wanfang Data. In addition, ongoing trials will be retrieved from the WHO ICTRP Search Portal, the Chinese Clinical Trial Register and The Clinical Trials Register.

A comparison of the efficacy and safety of complementary and alternative therapies for gastroesophageal reflux disease: A protocol for network meta-analysis.

Background: Gastroesophageal reflux disease (GERD) is one of the most common gastrointestinal diseases in the world and is showing increasing prevalence in some countries. The disease has a chronic course that leads to a significant decline in the quality of life of patients and is associated with a high economic burden worldwide. And complementary and alternative medicine is used to treat the disease.

Electrostatically mediated layer-by-layer assembly of nitrogen-doped graphene/PDDA/gold nanoparticle composites for electrochemical detection of uric acid.

A layer-by-layer self-assembled nitrogen-doped graphene/PDDA/gold nanoparticle (NDG/PDDA/GNP) composite was described. Citrate-stabilizing gold nanoparticle colloids (GNPs) were electrostatically adsorbed onto NDG nanosheets using a cationic polyelectrolyte, polydiallyldimethylammonium (PDDA), as the linker, thereby creating a high-performance electrochemical interface. The morphology and chemical composition were characterized by scanning electron microscopy, transmission electron microscopy, X-ray photoelectron spectroscopy, ultraviolet-visible spectroscopy, infrared spectroscopy, and Raman spectroscopy.

Picosecond laser seal welding of glasses with a large gap.

Ultra-fast lasers can realize selective welding of glasses through nonlinear effect and have the advantages of having high welding accuracy, having small heat-affected zone, having high joint strength and not requiring intermediate absorption layer, which provides a new idea for chip packaging. However, this method is limited to the condition of optical contact, which is difficult to use in engineering applications. To solve this problem, an innovative seal welding method by picosecond laser is presented in this paper.

Robust adaptive motion/force control scheme for crawler-type mobile manipulator with nonholonomic constraint based on sliding mode control approach.

In this paper, a robust adaptive motion/force control (RAMFC) scheme is presented for a crawler-type mobile manipulator (CTMM) with nonholonomic constraint. For the position tracking control design, an adaptive sliding mode tracking controller is proposed to deal with the unknown upper bounds of system parameter uncertainties and external disturbances. Based on the position tracking results, a robust control strategy is also developed for the nonholonomic constraint force of CTMM.