Comparative study on static and dynamic digest characteristics of oat β-Glucan and β-Gluco-Oligosaccharides.

Both oat β-glucans (OGs) and their hydrolyzed counterparts, oat β-gluco-oligosaccharides (OGOs), are dietary fibers indigestible by humans. They serve as substrates for the colonic intestinal flora, exhibiting potential prebiotic properties. This study, through in vitro digestion simulation, found that OGs and OGOs are not degraded and can safely pass through the upper digestive tract to reach the colon.

Advances in molecular enzymology of β-1,3-glucanases: A comprehensive review.

β-1,3-Glucanases are essential enzymes involved in the hydrolysis of β-1,3-glucans, with significant biological and industrial relevance. These enzymes are derived from diverse sources, including bacteria, fungi, plants, and animals, each exhibiting unique substrate specificities and biochemical properties. This review provides an in-depth analysis of the natural sources and ecological roles of β-1,3-glucanases, exploring their enzymatic properties such as optimal pH, temperature, molecular weight, isoelectric points, and kinetic parameters, which are crucial for understanding their functionality and stability.

L-Fucose increases the fucosylation of colorectal cancer cells promoting the accumulation of serine.

Fucosylation, a kind of posttranslational modification, has been identified as a key regulator of health, with alterations in this process serving as an indicator of diseases such as colorectal cancer. L-Fucose, an essential substrate of fucosylation, was reported to possess anticancer potential and increase fucosylation. However, the association between its tumour-inhibitory effect and its ability to regulate fucosylation was not fully understood.