Publications by authors named "Zenglu Ma"

Article Synopsis
  • The study aimed to explore how interferon regulatory factor 4 (IRF4) is expressed and how it relates to inflammation during secondary injury in cases of intracerebral hemorrhage (ICH).
  • A rat model was created by injecting collagenase into the brain, and findings showed a significant increase in IRF4 expression and inflammatory cytokines (IL-1b and IL-6) in ICH-affected rats compared to controls.
  • This research suggests that higher IRF4 levels are associated with increased inflammation in ICH, providing a potential target for future clinical treatments.
View Article and Find Full Text PDF

Mesenchymal stromal injection is a promising therapy for traumatic brain injury (TBI). The aim of this study was to explore the effects of the HIF-1α/SDF-1/CXCR4 axis on neuron repair in TBI rats through improving the bone marrow-derived mesenchymalstromal cells (BMSCs) migration. TBI rat models were established.

View Article and Find Full Text PDF

Background: Hypertensive cerebral hemorrhage (HCH) is a potentially life-threatening neurological condition with an extremely high morbidity and mortality. In recent years, neuroendoscopy has been used to treat intracerebral hemorrhage (ICH). However, the choice of neuroendoscopic surgery versus craniotomy for patients with intracerebral hemorrhages is controversial.

View Article and Find Full Text PDF