Accuracy of Percutaneous Pedicle Screw Placement Using Modified Single Anterior-Posterior Fluoroscopy with the C-Arm for the Treatment of Traumatic Thoracic and Lumbar Fractures.

Objective: We aimed to assess percutaneous pedicle screw (PPS) placement accuracy, fluoroscopy shot number, and operation time using a modified single anterior-posterior (AP) fluoroscopy with a C-arm in treating traumatic thoracic and lumbar vertebral fractures.

Methods: In total, 164 patients with single-level traumatic thoracic or lumbar fracture who underwent 6 PPS placements between April 2018 and September 2020 were divided into 2 groups. Conventional AP combined lateral fluoroscopy was used in Group A, whereas modified single AP fluoroscopy was used in Group B.

Illumination Intelligent Adaptation and Analysis Framework: A comprehensive solution for enhancing nighttime driving fatigue monitoring.

Nighttime driving presents a critical challenge to road safety due to insufficient lighting and increased risk of driver fatigue. Existing methods for monitoring driver fatigue, mainly focusing on behavioral analysis and biometric monitoring, face significant challenges under low-light conditions. Their effectiveness, especially in dynamic lighting environments, is limited by their dependency on specific environmental conditions and active driver participation, leading to reduced accuracy and practicality in real-world scenarios.

Simulation study on creep deformation of the impeller in lead-bismuth eutectic environment through fluid-solid coupling method.

Lead-based reactor is a new type of reactor using liquid lead or lead-bismuth alloy as a coolant. As the core working element of the main pump, the impeller is subjected to a huge load when conveying heavy metal liquids and is highly susceptible to damage. In this study, we used ANSYS and FLUENT software to investigate the stress, deformation, and creep deformation of the nuclear main pump impeller under a liquid lead-bismuth environment by the fluid-solid coupling method.

Exploring the mechanism of Astragali radix for promoting osteogenic differentiation based on network pharmacology, molecular docking, and experimental validation.

The present study used network pharmacology and molecular docking to predict the active ingredients and mechanisms of action of Astragalus radix (AR) to promote osteogenic differentiation of bone marrow mesenchymal stem cells (BM-MSCs), and cell experiments were conducted for verification. First, network pharmacology was used to predict the effective components, targets, and mechanisms of action of AR to promote osteogenic differentiation. The effective components and corresponding target proteins of AR, and the target proteins of osteogenic differentiation were collected through the database.

Cellular senescence of renal tubular epithelial cells in renal fibrosis.

Renal fibrosis (RF) is the common pathological manifestation of virtually all chronic kidney diseases (CKD) and one of the major causes of end-stage renal disease (ESRD), but the pathogenesis of which is still unclear. Renal tubulointerstitial lesions have been identified as a key pathological hallmark of RF pathology. Renal tubular epithelial cells are the resident cells of the tubulointerstitium and play an important role in kidney recovery versus renal fibrosis following injury.

Understanding the mechanism of twenty-five ingredient decoction for setting a fracture in the treatment of fractures based on network pharmacology.

To study the mechanism of 25 ingredient decoction for setting a fracture (TDSF) in fracture treatment using network pharmacology. The TCMSP, BATMAN-TCM, HERB, and Uniprot protein databases were used to identify the active ingredients and targets of TDSF. Fracture-related targets were collected from the gene cards and the online mendelian inheritance in man databases.

Anti-apoptotic effect of HeidihuangWan in renal tubular epithelial cells via PI3K/Akt/mTOR signaling pathway.

Ethnopharmacological Relevance: Heidihuang Wan (HDHW) is a classic Chinese herbal formula, which was first recorded in the "Suwen Bingji Qiyi Baoming Collection" written by Liu Wansu during the Jin Dynasty (1115-1234 AD). It is commonly used clinically for the treatment of kidney diseases and its curative effect is stable. Previous animal experiments have confirmed that HDHW can effectively improve renal fibrosis.

Heidihuangwan alleviates renal fibrosis in rats with 5/6 nephrectomy by inhibiting autophagy.

Renal fibrosis is a common pathway for the progression of various chronic kidney diseases (CKD), and the formation and deterioration will eventually lead to end-stage renal failure, which brings a heavy medical burden to the world. HeidihuangWan (HDHW) is a herbal formulation with stable and reliable clinical efficacy in the treatment of renal fibrosis. However, the mechanism of HDHW in treating renal fibrosis is not clear.

Ethnic discordance in serum anti-Müllerian hormone in healthy women: a population study from China and Europe.

Research Question: Chinese women are known to have an earlier age of natural menopause than their European counterparts, but whether they also have a lower functional ovarian reserve is unknown. This study was designed to assess whether there are ethnic differences in anti-Müllerian hormone (AMH) concentrations in women of reproductive age.

Design: Women in China and Europe with regular menstrual cycles, not on hormonal contraception and with no medical history of note, were recruited to provide a day 2-5 early follicular phase sample.