[Relationships among interleukin-1beta, interleukin-1 receptor antagonist gene polymorphism and susceptibility to gastric cancer].

Objectives: To investigate the genetic polymorphisms of interleukin-1B (IL-1B) and interleukin-1 receptor antagonist gene (IL-1RN) in gastric cancer, and to explore the relationships of these genetic polymorphisms to the susceptibility of gastric cancer.

Methods: The polymorphisms of IL-1B and IL-1RN genes were analyzed by PCR-restriction fragment length polymorphism (PCR-RFLP) after extracting the genomic DNA from 140 gastric cancer patients and 165 age- and sex-matched healthy controls.

Results: The polymorphisms of IL-1B promoter region -31, -511 and +3954 locus have no significant difference between gastric cancer patients and healthy subjects.

[A prospective study on quality of life in post-operative colorectal cancer patients with fast-track].

Objective: To explore the impact of postoperative recovery and short term quality of life in the patients with colorectal cancer in fast track model.

Methods: There were 122 patients enrolled into this prospective study in Gastrointestinal Surgery Center, West China Hospital of Sichuan University, from October 2008 to January 2009, and 121 patients completed the whole study. The patients were divided into the fast track group (62 cases) and the tradition track group (59 cases), postoperative recovery and the QLQ-C30 scores were evaluated at one week after the surgery.

[Impact of mesorectal involvement on the outcome of patients with rectal cancer].

Objective: To assess the relationship between the incidence and prognostic significance of mesorectal involvement.

Methods: 328 cases of rectal cancer resected with total or subtotal mesorectal excision in our hospital from Jan. 1997 to Dec.