Publications by authors named "Zeng-Hui Mao"
Article Synopsis
- Polycystic ovary syndrome (PCOS) is a complex disorder involving high androgen levels, irregular ovulation, and specific ovarian structures, with metabolites possibly influencing its variations.
- Previous research has utilized SNPs (single nucleotide polymorphisms) to establish causal relationships between metabolites and phenotypes in PCOS, identifying several metabolites that either influence or are influenced by the condition.
- The findings of this study suggest potential new insights into the biological mechanisms behind PCOS and highlight the need for further research on the use of these metabolites as clinical biomarkers for diagnosis and prediction.
Dozens of loci associated with fracture have been identified by genome-wide association studies (GWASs). However, most of these variants are located in the noncoding regions including introns, long terminal repeats, and intergenic regions. Although combining regulation information helps to identify the causal SNPs and interpret the involvement of these variants in the etiology of human fracture, regulation information which was truly associated with fracture was unknown.
View Article and Find Full Text PDFObjective: Diminished ovarian reserve (DOR) can lead to early menopause, poor fecundity, and an increased risk of disorders such as osteoporosis, cardiovascular disease, and cognitive impairment, seriously affecting the physical and mental health of women. There is still no safe and effective strategy or method to combat DOR. We have developed a novel Chinese herbal formula, Tongji anti-ovarian aging 101 (TJAOA101), to treat DOR.
View Article and Find Full Text PDF[Analysis of 92 ectopic pregnancy patients after in vitro fertilization and embryo transfer].
Zhong Nan Da Xue Xue Bao Yi Xue Ban
August 2006
Objective: To investigate the occurrence of ectopic pregnancy among women who received in vitro fertilization and assess the influential factors.
Methods: The indications, methods of assisted conception and ectopic types were analyzed retrospectively after the patients received in vitro fertilization and embryo transfer (IVF-ET), intracytoplasmic sperm injection (ICSI), or freezing-thawing embryo transfer (FET).
Results: A total of 6007 embryo transfers were performed, and 2322 (38.