Publications by authors named "Zena Slim"

Article Synopsis
  • Confocal laser endomicroscopy (CLE) is a non-invasive technology that allows real-time visualization of cellular structures for diagnosing oral epithelial dysplasia (OED) and oral squamous cell carcinoma (OSCC).
  • A study involving 47 patients used a handheld fluorescence single-fibre distal-scanning CLE system to compare its optical diagnoses against traditional tissue biopsy analyses, resulting in a high diagnostic accuracy of 88.9%.
  • The fsdCLE technology is shown to be effective and user-friendly for clinicians, accurately identifying all carcinoma cases and providing reliable differentiation between dysplastic and non-dysplastic conditions.
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Embryonal rhabdomyosarcoma of the uterine cervix is a rare neoplasm which is almost invariably associated with pathogenic somatic or germline DICER1 mutations; patients with germline mutations have DICER1 syndrome. We report 2 subtle cervical embryonal rhabdomyosarcoma, one occurring in a 21-yr-old woman with a known history of DICER1 syndrome and the other in a 19-yr-old woman with no history of DICER1 syndrome or DICER1-associated neoplasms. Both neoplasms focally involved otherwise benign endocervical polyps and were characterized histologically by subtle areas of increased stromal cellularity, nuclear atypia and mitotic activity; there was focal nuclear staining of these areas with the skeletal muscle markers myogenin and myoD1.

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