Publications by authors named "Zena Chakim"

Over the last years, there has been an increasing number of proposals for the use of nanomaterials in medicine. The safety of novel technologies must be verified, prior to their clinical application. Pathology has much to contribute towards this end.

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Background Cataract surgery is a very popular operation that requires a postoperative period of frequent instillation of antibiotic and anti-inflammatory eye drops. Modified drug-eluting intraocular lenses (IOLs) may eliminate the need for eye drops after surgery. Aim The purpose of this study is to compare the morphological characteristics of dexamethasone eluting biodegradable polymeric thin films developed on the surface of commercially available IOLs by three different methods.

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Article Synopsis
  • Researchers developed water-in-oil (W/O) microemulsions using refined olive oil or sunflower oil, distilled monoglycerides, and ethanol to effectively carry the antimicrobial substance nisin for biopreservation.
  • The study provided insights into how factors like ethanol concentration and the type of oil influence the size and structure of the microemulsions, with findings from multiple advanced techniques such as SAXS and EPR spectroscopy.
  • The antimicrobial activity of nisin was tested against Lactococcus lactis and showed effectiveness, especially at higher ethanol levels, but there was no significant difference in performance between the two types of oil used.
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