[Therapy of primary brain tumors with segidrin].

The results of segidrin administration to 46 patients with malignant and 6 patients with benign tumors of the brain are presented. Pronounced therapeutic effect for the whole group was 63.5% and 73%, if partial regression of neurologic symptoms in the entire brain and separate foci is considered.

[The surgical treatment procedure and results in multifocal epilepsy].

Various methods of surgical intervention were applied differentially in 116 patients with multifocal epilepsy. From analysis of the late-term results it was found that the cortical form of multifocal epilepsy is treated most effectively by open and the cortico-subcortical form--by combined operations (use of stereotaxis during an open operation). The most rational operations in bitemporal epilepsy are bilateral one-stage stereotaxic interventions on the mediobasal temporal structures or successive (at various intervals) performance of stereotaxic operation on one temporal lobe and open operation on the contralateral temporal lobe.

[Epidurography in lesions of the lumbar intervertebral disks].

Operations were carried out on 850 patients with neurological complications of lumbar osteochondrosis. Epidurography with 35-40% verografin solution was conducted before the operation in 795 patients. The method is described.

[Various aspects of the development of the problem of the diagnosis and surgery of cranio-cerebral injuries].

Modern principles of diagnosis and specific treatment of different kinds of cranio-cerebral traumas are elucidated on the basis of the authors' personal experience and literature data.

[Neurinomas of the acoustic nerve in childhood and adolescence].

The specific features of neurinoma of the auditory nerve were analysed clinically in 21 patients whose ages ranged from 12 to 18 years. Neurinoma of the auditory nerve located in the cerebellopontine area in children and adolescents has some specific features distinguishing it from that in adults. For instance, its incidence among boys is the same as that among girls.

[Congenital brain tumors in children under 1 year old].

Secondary, paraventricular and, less frequently, primary tumors of the lateral and third ventricles usually of supratentorial localization prevailed among congenital tumors of the brain. They impair the drainage of cerebrospinal fluid and cause internal hydrocephalus. The clinical picture of congenital cerebral tumors is characterized by a manifest hypertensive-hydrocephalic syndrome and a severe general condition.

[Basic criteria for evaluating the clinical variants of aggressive behavior disorders in epileptics].

On the basis of the case histories of patients suffering from epilepsy with aggressive manifestations and an analysis of reported data the authors describe a syndrome of aggressive behavioural disturbances (ABD) in epileptics and the basic criteria for evaluating the numerous clinical variants of this syndrome which may be divided into the following groups: (1) criteria for assessing the degree of severity of the ABD clinical course; (2) criteria for assessing the function of patients with ABD; (3) criteria for assessing the relationship between ABD and other clinical manifestations of epilepsy. The use of these criteria makes it possible to (a) ascertain the topical-diagnostic importance of individual variants of ABD; (b) specify differential indications for surgical intervention; (c) carry out a comparative evaluation of the results of conservative and surgical treatment of epilepsy aimed at correcting ABD.

[Clinical features of pituitary chromophobe adenomas in school-age children].

The work is based on 20 cases of hypophyseal chromophobe adenoma in children of school age. The incidence of hypophyseal chromophobe adenomas grows with age. In distinction from adults, the disease in children follows a more rapid course and usually begins with visual disorders and less frequently with endocrine and metabolic disorders.

[Clinico-electrophysiologic analysis of the results of surgical treatment of focal epilepsy in children].

The authors analyzed the electroclinical data obtained in the surgical treatment by the open method of 104 children and adolescents with focal and multifocal epilepsy. The indications were frequent epileptic seizures, resistance to drug therapy, clear-cut clinical and electrophysiological correlations with regard to the localization of the epileptic focus. If nonoperative treatment has no effect, it is not advisable to delay surgical intervention by more than 1--2 years.

[Clinical picture, diagnosis, and surgical treatment of multifocal epilepsy in children].

The work analyses 328 cases of epilepsy in children 114 of whom had multifocal epilepsy. The specific features of the clinical course of multifocal epilepsy and the findings of complex examination are presented. In view of the difficulties in making the diagnosis of multifocal epilepsy and, particularly, in determining the localization of the foci of epileptic activity in the cortical and subcortical brain structures, besides the commonly accepted methods of epilepsy management, the authors used a combined method which allowed intraoperative study of the bioelectric activity not only of the cortex but simultaneously of the subcortical structures by stereotaxis; on basis of the findings they determined the character and volume of the intervention.

[Examination of conduction by injured nerves in children].

Increase of skin resistance in Ohms to 828--1000 kOhm, reduction of temperature by 1.4 +/- 0.5--2.

[N.N. Burdenko and certain aspects of development of Russian neurosurgery].

The authors point out the outstanding merits of academician N. N. Burdenko in the organization and development of national neurosurgery, and also tremendous successes achieved by soviet specialists of neurosurgery in the diagnosis and treatment of mono- and multifocal epilepsy, cerebral vascular lesions, brain tumors in adults and children, craniocerebral trauma.

[The clinical picture of spinal cord tumors with different histostructures in children].

An analysis into the results of treatment accorded to 101 sick children wiht tumours of the spinal cord evidences that the clinical picture of this pathology is distinguished by a number of features that depend on the histological structure, high compensatory potentialities and extraordinary plasticity of the child's spinal cord and vertebral column. In this connection of prime importance becomes the significance of assessing the data derived from a comprehensive examination, due consideration being given to the age-specific features of the patients. As concerns their incidence in children first and foremost are tumours of the glial series, distinguished by a comparatively mild course of the disease, paucity of focal and conduction symptomatology that is incongrous with the extent of the lesion involving the spinal cord both along its vertical and transverse section.

[Use of stereotaxic method in combination with classic craniotomy in treatment of focal epilepsy].

A new method of surgical treatment in dealing with severe forms of multifocal epilepsy-stereotaxic intervention on subcortical structures during open craniotomy--is proposed. The method allows stereoelectrographic examinations to be performed during open operative interventions, helps discover subcortical epileptogenic foci, establish functional interrelationship of the chosen subcortical structure and the cortical epileptogenic focus and to undertake a differentiated intervention on the cortical, subcortical and both these foci at the same time.