Publications by authors named "Zemeng Xiao"
Article Synopsis
- Ferroptosis, a type of cell death, is responsible for heart damage caused by the cancer drug doxorubicin (DOX), which affects key proteins involved in cell protection.
- The study found that hydrogen sulfide (HS) can protect heart cells from DOX-induced damage by restoring important proteins, like GPX4 and NFS1, and reducing harmful lipid peroxidation.
- Additionally, HS works by interacting with a protein called OPA3, which is crucial for preventing heart cell death, highlighting a potential new treatment strategy to mitigate DOX's cardiotoxic effects.
