Evaluation of anti-nociceptive and anti-inflammatory activities of solvent fraction of the roots of Mesfin (Asteraceae) in mice model.

Objective: The present study was aimed at investigating the antinociceptive and anti-inflammatory activities of the solvent fractions of the roots of  Mesfin in rodent models of pain and inflammation.

Methods: Successive maceration was used as a method of extraction using solvents of increasing polarity: methanol and water. Ethyl acetate, chloroform and distilled water were used as solvents of the fraction process.