Publications by authors named "Zemei Liu"

Some skin wounds often have many exudate. Ordinary single layer electrospunning nanofiber wound dressings often don't have enough capacity to absorb them. Therefore, a separable double layer electrospunning nanofiber dressing was developed in this work.

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In this study, multivesicular liposomes (MVLs) were prepared by microfluidic technology and used for delivering gastrodin (GAS), a water-soluble drug, across the blood-brain barrier (BBB). The formulations and preparation parameters in preparing gastrodin multivesicular liposomes (GAS-MVLs) were both optimized. Some properties of GAS-MVLs including morphology, particle size, encapsulation efficiency, and release were evaluated.

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Objective: In order to improve the dissolution property of quercetin (QCT), the quercetin nanocrystals (QNCs) were prepared in this study.

Methods: QNCs were prepared by a 100 μm diameter Y-shape microfluidic channel. Some impact factors affecting the generation of QNCs such as concentration and flow rate were investigated.

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The ideal wound dressing should adequately protect the wound from bacterial infection and provide a suitable healing environment for the wound. Thus, we prepared a biodegradable functional nanofiber dressing with good antibacterial and biocompatibility by electrospinning technology. The average diameter of the dressing was 354 ± 185 nm, and the porosity was 93.

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Objecteives: The purpose of this study was to prepare an antibacterial, antioxidant, and biocompatible bilayer nanofibrous wound dressing by using electrospinning.

Methods: The micromorphology and bilayer structure characteristics of the GA-Qe-PVP-PCL nanofibers were analyzed by SEM. The physicochemical characteristics were analyzed by XRD and FTIR.

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Bipolar host materials with high triplet energy are of great significance for highly efficient blue organic light-emitting diodes (OLEDs). In this work, three donor-acceptor-donor (D-A-D) type host materials with identical non-rigid diphenylsulfone center but differing in rotation degree of peripheral amino substituted derivatives from rotating freely diphenylamine (SODP) to rotating partially iminodibenzyl (SOId) and rotating restricted carbazole (SOCz) were designed and synthesized. It was demonstrated that the triplet energy (E ) level of the materials promoted by limiting the rotation degree of the peripheral groups, which was 2.

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Herein, structured non-doped white organic light-emitting diodes (WOLEDs) were designed by combining the emission of a blue exciplex and orange-red phosphorescent ultrathin layer. The device efficiency and spectra were modulated successfully by adjusting the thickness of the exciplex layer and ultrathin layer, respectively. Meanwhile, high efficiency with external quantum efficiency (EQE) ranging from 15% to 22%, power efficiency from 33 lm W to 47 lm W and warm white emission with correlated color temperature (CCT) from 1600 K to 2600 K were realized.

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Synopsis of recent research by authors named "Zemei Liu"

  • - Zemei Liu's recent research predominantly focuses on developing biomedical materials and drug delivery systems, particularly nanofibrous wound dressings and multivesicular liposomes for enhanced therapeutic efficacy in wound healing and drug transport across biological barriers.
  • - Key findings include the creation of a double-layer self-pumping dressing that improves moisture management for wound healing, and optimized microfluidic preparation methods for multivesicular liposomes facilitating oral delivery of gastrodin, a water-soluble drug, across the blood-brain barrier.
  • - Liu's work also explores the enhancement of dissolution properties of bioactive compounds like quercetin through nanocrystal formulation, aiming to increase their bioavailability, as well as investigating biodegradable materials for wound care that exhibit antibacterial and antioxidant properties.