Investigating the Mechanical Characteristics and Fracture Morphologies of Basalt Fiber Concrete: Insights from Uniaxial Compression Tests and Meshless Numerical Simulations.

To explore the mechanical properties and fracture modes of basalt fiber-reinforced concrete, single-doped and hybrid-doped basalt fiber-reinforced concrete was prepared, and uniaxial failure tests under different basalt fiber-reinforced concrete contents were carried out. At the same time, the smooth kernel function in the traditional SPH method was improved, and the basalt fiber random generation algorithm was embedded in the SPH program to realize the simulation of the progressive failure of basalt fiber-reinforced concrete. The results show that under the circumstance with no basalt fiber, the specimen final failure mode is damage on the upper and lower surface, as well as the side edge, while the interior of the specimen center is basically intact, indicating that there is an obvious stress concentration phenomenon on the upper and lower surface when the specimen is compressed.

Identification and analysis of flavonoid pathway genes in responsive to drought and salinity stress in Medicago truncatula.

Flavonoid compounds are widely present in various organs and tissues of different plants, playing important roles when plants are exposed to abiotic stresses. Different types of flavonoids are biosynthesized by a series of enzymes that are encoded by a range of gene families. In this study, a total of 63 flavonoid pathway genes were identified from the genome of Medicago truncatula.

Crosstalk between CXCL12/CXCR4/ACKR3 and the STAT3 Pathway.

The reciprocal modulation between the CXCL12/CXCR4/ACKR3 axis and the STAT3 signaling pathway plays a crucial role in the progression of various diseases and neoplasms. Activation of the CXCL12/CXCR4/ACKR3 axis triggers the STAT3 pathway through multiple mechanisms, while the STAT3 pathway also regulates the expression of CXCL12. This review offers a thorough and systematic analysis of the reciprocal regulatory mechanisms between the CXCL12/CXCR4/ACKR3 signaling axis and the STAT3 signaling pathway in the context of diseases, particularly tumors.

High incidence of gallstones after Roux-en-Y reconstruction gastrectomy in gastric cancer: a multicenter, long-term cohort study.

Background: Roux-en-Y reconstruction is a common anastomosis technique during gastrectomy in gastric cancer. There is a lack of studies on gallstones after Roux-en-Y reconstruction gastrectomy. This study investigated the incidence and potential risk factors associated with gallstones after Roux-en-Y reconstructive gastrectomy in gastric cancer.

The gut microbiome dysbiosis and regulation by fecal microbiota transplantation: umbrella review.

Background: Gut microbiome dysbiosis has been implicated in various gastrointestinal and extra-gastrointestinal diseases, but evidence on the efficacy and safety of fecal microbiota transplantation (FMT) for therapeutic indications remains unclear.

Methods: The gutMDisorder database was used to summarize the associations between gut microbiome dysbiosis and diseases. We performed an umbrella review of published meta-analyses to determine the evidence synthesis on the efficacy and safety of FMT in treating various diseases.

Excitonic solar cells based on van der Waals heterojunctions of Janus III-VI chalcogenide monolayers.

We construct the two-dimensional (2D) excitonic solar cells based on type II vdW heterojunctions of Janus III-VI chalcogenide monolayers and investigate the performance of the device using the first principle. The calculated solar energy absorbance of InSSe/GaInSeand InSeTe/GaInSeheterojunctions is the order of 10cm. The predicted photoelectric conversion efficiency of the InSeTe/GaInSeheterojunction can reach up to 24.

Senescent Fibroblasts Generate a CAF Phenotype through the Stat3 Pathway.

Aging has been recently reported to promote lung cancer initiation and progression. Senescent fibroblasts gain a cancer-associated fibroblast (CAF) phenotype, and exert a powerful influence on cancer behavior, such as tumor cell growth and metastasis. However, mechanisms linking fibroblast senescence with CAF activation remain poorly understood.

Generating Daily Soil Moisture at 16 m Spatial Resolution Using a Spatiotemporal Fusion Model and Modified Perpendicular Drought Index.

Soil moisture (SM) is an important parameter in land surface processes and the global water cycle. Remote sensing technologies are widely used to produce global-scale SM products (e.g.

Fault Diagnosis and Handling of the Two-Dimensional Tracking Servo System for Space.

Aiming at the on-orbit safety problem of the two-dimensional tracking servo system for space, based on ant colony optimization (ACO) and expert systems, this paper proposes a fault diagnosis and handling strategy of the two-dimensional (2D) tracking servo system for space. Specifically, a fault library was established for the tracking servo system according to field observations. The ACO was called to optimize the classification of fault features.

Screening and functional identification of antioxidant microRNA-size sRNAs from Spirulina platensis using high-throughput sequencing.

MiRNA-size small RNAs, abbreviated as sRNAs, are increasingly being discovered as research progresses and omics technologies development in prokaryotes. However, there is a paucity of data concerning whether or not sRNAs exist in cyanobacteria and regulate the resistance to oxidative stress. In this investigation, small RNA libraries were constructed from the control, 50-nM and 100-nM H2O2 treatments of Spirulina platensis.

Tunable spatiotemporal mode-locked fiber laser at 1.55 μm.

We report the spatiotemporal mode-locked multimode fiber laser operating at 1.55 µm based on semiconductor saturable absorber mirrors with the mode-locking threshold as low as 104 mW. Benefiting from the multimode interference filtering effect introduced in the laser cavity not only the central wavelength can be continuously tuned from 1557 nm to 1567 nm, but also the number of the output pulses can be adjusted from 1 to 4 by simply adjusting the polarization controllers.

Serial-tilted-tapered fiber with high sensitivity for low refractive index range.

We propose an optical fiber sensor for low refractive index (RI) based on a serial-tilted-tapered fiber (STTF), which can be considered as two tightly concatenated micro Mach-Zehnder interferometers (MZIs). The STTF has a compact length of 959.8 μm, and can realize point detection and sensing in limited space.

Fast auto-focusing search algorithm for a high-speed and high-resolution camera based on the image histogram feature function.

In this paper, we developed an auto-focus image quality evaluation function from the histogram feature function (HFF) of a high-speed camera. Based on this function, we then proposed a fast auto-focus search algorithm. We further demonstrated that the auto-focus image quality evaluation function we proposed requires fewer computational resources, while providing a more effective focusing area and more moderate sensitivity, compared to the traditional evaluation function.

Dicer1/miR-29/HMGCR axis contributes to hepatic free cholesterol accumulation in mouse non-alcoholic steatohepatitis.

Dicer1 is an enzyme essential for microRNA (miRNA) maturation. The loss of miRNAs resulted from Dicer1 deficiency greatly contributes to the progression of many diseases, including lipid dysregulation, but its role in hepatic accumulation of free cholesterol (FC) that is critical in the development of non-alcoholic steatohepatitis (NASH) remains elusive. In this study, we used the liver-specific Dicer1-knockout mice to identify the miRNAs involved in hepatic FC accumulation.

MicroRNA-1304 suppresses human non-small cell lung cancer cell growth in vitro by targeting heme oxygenase-1.

Previous studies have shown that microRNA-1304 (miR-1304) is dysregulated in certain types of cancers, including non-small cell lung cancer (NSCLC), and might be involved in tumor survival and/or growth. In this study we investigated the direct target of miR-1304 and its function in NSCLC in vitro. Human lung adenocarcinoma cell lines (A549 and NCI-H1975) were studied.

pKILLIN: a versatile positive-selection cloning vector based on the toxicity of Killin in Escherichia coli.

The invention of DNA cloning over 40 years ago marked the advent of molecular biology. The technique has now become a routine practice in any modern biomedical laboratory. Although positive-selection of recombinants in DNA cloning seems to be superior to blue/white selection based on the disruption of the lacZ gene, it is rarely practiced due to its high background, lack of multiple cloning sites, and inability to express the genes of interest or purify the protein products.

[Differences in the changes of blood clotting state after initial trauma fractures and twice trauma fractures].

Objective: To compare changes of blood clotting state after initial trauma fractures and twice trauma fractures, investigate the effect of fracture history to the state of the blood clotting after secondary trauma fractures.

Methods: Thirty New Zealand rabbits were selected, aged 5-6 months, males and females unlimited, weighted 2.4-2.