Publications by authors named "Zeliha K Tufan"

Article Synopsis
  • - The study assessed the effectiveness of ertapenem vs. meropenem in treating bacteremia caused by ESBL-producing bacteria in kidney transplant recipients, using a large cohort from 29 international centers.
  • - Among the 201 patients, clinical cure rates at day 14 were similar: 45% for ertapenem and 50.5% for meropenem, indicating that both treatments are comparable in effectiveness.
  • - Additionally, over 49% of patients treated with ertapenem showed better outcomes when considering factors like hospital stay and cost, suggesting that ertapenem might offer some advantages over meropenem in this context.
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Objectives: We evaluated the treatment outcome in late acute (LA) periprosthetic joint infections (PJI) treated with debridement and implant retention (DAIR) versus implant removal.

Methods: In a large multicenter study, LA PJIs of the hip and knee were retrospectively evaluated. Failure was defined as: PJI related death, prosthesis removal or the need for suppressive antibiotic therapy.

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Factors influencing treatment outcome of patients with Gram-negative bacterial (GNB) multidrug-resistant (MDR) and extensively drug-resistant (XDR) prosthetic joint infection (PJIs) were analysed. Data were collected (2000-2015) by 18 centres. Treatment success was analysed by surgery type for PJI, resistance (MDR/XDR) and antimicrobials (colistin/non-colistin) using logistic regression and survival analyses.

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Objectives: Debridement, antibiotics and implant retention (DAIR) is the recommended treatment for all acute prosthetic joint infections (PJI), but its efficacy in patients with late acute (LA) PJI is not well described.

Methods: Patients diagnosed with LA PJI between 2005 and 2015 were retrospectively evaluated. LA PJI was defined as the development of acute symptoms (≤ 3 weeks) occurring ≥ 3 months after arthroplasty.

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Crimean Congo hemorrhagic fever (CCHF) is a viral zoonotic disease with high mortality rate. There are only a few studies on viral load in CCHF. In our study, we revealed the dynamics of viral load and its relationship with mortality in early phase of the disease.

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Article Synopsis
  • Entecavir (ETV) and tenofovir disoproxil fumarate (TDF) are two medicines used to treat chronic hepatitis B and both are very effective at fighting the virus.
  • In a study with 252 patients from 6 different places, those taking ETV had better early results in lowering virus levels, but TDF overall was better at completely stopping the virus.
  • While ETV showed faster results in the first year, TDF was found to be more successful in the long run for completely controlling the virus.
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Background: Viral conjunctivitis are the most frequent infections in ophthalmology clinics. The diagnosis is usually relying on clinical findings and medical history. However, topical antibiotics are often used unnecessarily addition to symptomatic treatment because of unsure agents.

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Objectives: Crimean Congo hemorrhagic fever (CCHF) is the second most common hemorrhagic fever worldwide. This study aimed to evaluate the oxidant-antioxidant balance of patients with CCHF by detecting dynamic thiol disulfide homeostasis (TDH), which is a novel oxidative stress marker, and other molecules, including paraoxonase (PON), arylesterase (ARES), ceruloplasmin (CLP), myeloperoxidase (MPO), and catalase.

Methods: This retrospective, cross-sectional, controlled study, which involved patients with CCHF and healthy volunteers, measured dynamic TDH using a novel automated method developed by Erel.

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Objectives: Sepsis is a severe condition with possible high mortality outcomes. A multicentre-survey to detect the knowledge of the physicians who are involved in sepsis management in daily work was conducted.

Materials And Methods: The study was held in October 2013.

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Objectives: Crimean-Congo hemorrhagic fever (CCHF) has been endemic in Turkey since 2002. Some radiologic findings are considered common by clinicians and radiologists. In this regard, we aimed to assess the sonographic findings in patents with CCHF in a pilot study to obtain basic knowledge for planning further controlled studies.

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Malaria is the fifth infection leading to death in the world. Plasmodium species is the malarial parasite that infects human cells. The five species of the human Plasmodium parasites are P.

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Background: Depressive symptoms and myalgia are commonly seen in patients with chronic hepatitis B and chronic hepatitis C.

Objective: To investigate the efficacy of acupuncture treatment on depressive symptoms and myalgia in patients with hepatitis.

Methods: Of 44 patients with hepatitis screened for depression and myalgia, 28 were enrolled and included in the study.

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The exact prevalence of Lyme disease caused by Borrelia burgdorferi is unknown in Turkey. However, B. burgdorferi seropositivity ranges between 6-44% among high risk groups.

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