Publications by authors named "Zelia Ines P Lobato"
Several studies have shown the occurrence of poxvirus infections associated with exanthematic lesions in cattle from many Brazilian states. Coinfection between viruses belonging to 2 genera, Orthopoxvirus (OPXV) and Parapoxvirus (PPV), was already identified from the lesions of affected cows and humans. The DNA and infectious viral particles of Vaccinia virus, an OPXV, have been detected in milk of naturally and experimentally infected cows.
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- Vaccinia virus (VACV) causes bovine vaccinia (BV), a zoonotic disease impacting dairy cattle, prompting research into its clinical and biological effects on infected cows.
- In a study, lactating cows were infected with the VACV-GP2 strain, with some cows later divided into immunosuppressed and re-infection groups to analyze varied responses to the virus.
- Findings revealed that experimental infection induced similar symptoms to natural infections, including short incubation periods and notable lymphatic responses, alongside the presence of viral DNA in oral lesions, indicating possible reactivation in immunosuppressed animals.