Experimental investigation on the reverse mechano-electrical effect of porcine articular cartilage.

Introduction: The electric signals within the cartilage tissue are essential to biological systems and play a significant role in cartilage regeneration. Therefore, this study analyzed and investigated the reverse mechano-electrical effect in porcine articular cartilage and its related influencing factors.

Methods: The deflection of cartilage samples in an electric field was measured to analyze the mechanisms of different factors affecting the reverse mechano-electrical effect in articular cartilage.

Research progress on intervertebral disc repair strategies and mechanisms based on hydrogel.

Intervertebral disc degeneration (IDD) arises from a complex interplay of genetic, environmental, and age-related factors, culminating in a spectrum of low back pain (LBP) disorders that exert significant societal and economic impact. The present therapeutic landscape for IDD poses formidable clinical hurdles, necessitating the exploration of innovative treatment modalities. The hydrogel, as a biomaterial, exhibits superior biocompatibility compared to other biomaterials such as bioceramics and bio-metal materials.