Publications by authors named "Zekuan Xue"
The role of glycemic traits in the mediation of the causal effect of hypothyroidism on coronary heart disease.
Front Endocrinol (Lausanne)
October 2024
Article Synopsis
- This study investigated the causal link between hypothyroidism and coronary heart disease, finding a strong association but previously lacking definitive proof of causation.
- Using advanced statistical methods, the researchers confirmed that hypothyroidism increases the risk of coronary heart disease, with an odds ratio of 2.75, indicating a significant correlation.
- Additionally, they identified that glycemic traits, specifically HbA1c, partially mediate this relationship, suggesting that controlling blood sugar levels could help reduce heart disease risk in patients with hypothyroidism.