Association between the systemic immune-inflammation index and sarcopenia in older adults: a cross-sectional study.

Background: Chronic inflammation is increasingly recognized as a crucial contributor to sarcopenia pathogenesis, but accurate diagnosis remains a challenge.

Aim: Our study aims to investigate the relationship between sarcopenia and the Systemic Immune-Inflammation Index (SII), a comprehensive indicator of inflammation.

Methods: This cross-sectional study enrolled 632 patients.

Weight-Adjusted Waist Index: an anthropometric measure for frailty in older adults.

Purpose: Current measures of frailty often rely on subjective assessments or complex scoring systems. This study aims to investigate the utility of a novel anthropometric measure, the Weight-Adjusted Waist Index (WWI), as a simple and objective predictive marker for frailty in older adults.

Methods: This cross-sectional study included 847 patients aged 65 years and older.

Ultrasonographic/regional muscle measurements for diagnosing sarcopenia in older adults with and without dementia.

Background: Sarcopenia and dementia are growing concerns among older adults that muscle and brain atrophy may cooccur. We aimed to compare the age-related loss of muscle mass by using ultrasound (US), and skeletal muscle mass index (SMI) by bioelectrical impedance analysis in older adults with and without dementia.

Methods: A total of 221 older adults aged ≥65 years were included in the study.

Delirium, dementia, and depression (3D) assessment of older patients in the emergency department: 5-year survival analysis.

Background: While physicians tend to emphasize on physical medical problems, behavioral and cognitive disorders of geriatric patients are usually missed, especially in emergency settings. The aim of the study was to determine the prevalence of delirium, dementia, and depression (3D) among older patients (≥65 years old) in the Emergency Department (ED) and to evaluate the effect of geriatric 3D on the 6-month and 5-year mortality.

Methods: This was a prospective, observational cohort study, including 415 patients from eligible 512 consecutive older patients, who are 65 years of age or older, presenting to the ED of a tertiary care university hospital.

Best Practice Recommendations for Geriatric Dysphagia Management with 5 Ws and 1H.

Background: Dysphagia is a geriatric syndrome. Changes in the whole body that occur with aging also affect swallowing functions and cause presbyphagia. This condition may progress to oropharyngeal and/or esophageal dysphagia in the presence of secondary causes that increase in incidence with aging.

Turkish inappropriate medication use in the elderly (TIME) criteria to improve prescribing in older adults: TIME-to-STOP/TIME-to-START.

Purpose: To improve prescribing in older adults, criterion sets have been introduced from different countries. While current criterion sets are useful to some extent, they do not meet the need in some European countries. Turkish inappropriate medication use in the elderly (TIME) criteria was planned to meet this need.

The value of musculoskeletal ultrasound in geriatric care and rehabilitation.

The WHO reports that one of the major chronic conditions affecting the elderly worldwide is musculoskeletal disorders that are associated with long-term pain and disability. Considering the healthcare needs of the elderly (i.e.

Association of Bioelectrical Impedance Analysis-Derived Phase Angle and Sarcopenia in Older Adults.

Background: Sarcopenia is an important problem for older adults, leading to morbidity and mortality; therefore, early detection with a precise method is essential. We aimed to investigate the role of bioelectrical impedance analysis-derived phase angle as a determinant of sarcopenia.

Materials And Methods: A cross section of 263 community-dwelling and hospitalized older adults (>65 years) were assessed in terms of sarcopenia with bioelectrical indices and anthropometric measurements.

Serum markers of inflammation and oxidative stress in sarcopenia.

Background: Sarcopenia is a geriatric syndrome characterized by the presence of low muscle mass and function. Possible mechanisms underlying sarcopenia include oxidative stress and elevation of inflammatory cytokines.

Aims: The aim of the study was to evaluate the relationship between sarcopenia and biomarkers that may be involved in its pathogenesis and hence early detection.

Which parameters affect long-term mortality in older adults: is comprehensive geriatric assessment a predictor of mortality?

Background: Determining predictors of mortality among older adults might help identify high-risk patients and enable timely intervention.

Aims: The aim of the study was to identify which variables predict geriatric outpatient mortality, using routine geriatric assessment tools.

Methods: We analyzed the data of 1141 patients who were admitted to the geriatric medicine outpatient clinic between 2001 and 2004.

Is frailty a prognostic factor for critically ill elderly patients?

Aim: The study aimed to investigate the effects of frailty on clinical outcomes of patients in an intensive care unit (ICU).

Methods: In this prospective study, 122 patients (59 frail, 37 pre-frail and 26 robust) were included. A frailty index (FI) derived from comprehensive geriatric assessment parameters was used for the evaluation.

Nutritional issues in dementia patients.

Dementia is an inevitable disease of aging, leading not only to diminished cognitive ability but also behavioral changes, malnutrition, pressure sores, and infections. Acknowledging common problems and their solutions is essential for any health service worker who deals with demented geriatric patients.

Role of autophagy in the pathogenesis of Alzheimer disease.

Alzheimer disease (AD) is the most common progressive neurodegenerative disorder causing increased morbidity and mortality. It is characterized by accumulation of amyloid-β in neurons. As there is no known definitive treatment of this disorder, studies trying to determine its exact pathogenetic pathways and target therapies for these specific pathways are being rapidly conducted.

Estimating radiation therapy toxicity and tolerability with comprehensive assessment parameters in geriatric cancer patients.

Cancer prevalance and incidence is increasing with aging of populations and age is a critical factor in decision-making for anti-cancer treatment. However it is believed that chronological age is not enough to guide management in elderly cancer patients. Multidisciplinary evaluation and comprehensive geriatric assessment has gained importance regarding the treatment selection especially for definitive anti-cancer therapy recently.

Influence of antimuscarinic therapy on cognitive functions and quality of life in geriatric patients treated for overactive bladder.

Objectives: Incidences of overactive bladder (OAB) and cognitive dysfunction increase with aging. Treatment of OAB with antimuscarinic agents may result in cognitive decline, especially in patients with Alzheimer's disease (AD). The aim of this study is to evaluate the effect of antimuscarinic treatment on cognitive functions, depression, and quality of life (QOL) of patients with OAB.