Publications by authors named "Zekarias Gessessew Arefaine"
Am J Trop Med Hyg
July 2021
Article Synopsis
- The study assessed the effectiveness of a loop-mediated isothermal amplification (LAMP) assay for diagnosing visceral leishmaniasis (VL) in Ethiopia, showing a high sensitivity of 95.9% and specificity of 98.0%.
- LAMP demonstrated strong performance against existing methods, detecting 94.3% of microscopy-positive cases and 94.2% of rK39-positive cases, with particularly high sensitivity in HIV-positive patients (100%).
- Combining rK39 serology with LAMP could achieve a remarkable sensitivity of 99.2% and retains a specificity of 98.0%, showcasing LAMP as a rapid and reliable diagnostic option for VL, even in HIV co-in
