Prognostic value of computed tomography associated body composition measurement changes in metastatic colorectal cancer patients.

Background: Sarcopenia is associated with poor prognosis in metastatic colorectal cancer (mCRC) patients.

Purpose: To investigate the prognostic value of body composition measurement changes measured by computed tomography (CT) in mCRC patients.

Material And Methods: The abdominal skeletal muscle density (SMD) and skeletal muscle (SMI) indices, as well as the visceral (VATI) and subcutaneous fat tissue (SATI) indices, were calculated by automatic segmentation method on the abdominal CT images obtained before (n = 71) and after chemotherapy (n = 52).