Publications by authors named "Zejuan Ji"
Article Synopsis
- The study compared treatment outcomes for children with distal both-bone forearm fractures, focusing on whether fixing just the radius or both the radius and ulna was more effective.
- Analysis involved 71 patients, measuring factors like operation duration, reduction loss, and wrist function scores after treatment.
- Results showed that fixing only the radius resulted in similar clinical outcomes and wrist function compared to fixing both bones, suggesting it could be an effective treatment option.
Background: The purpose of this study was to investigate the clinical and functional outcomes of early versus delayed treatment of pediatric lateral condylar fractures of the humerus with a displacement greater than 2 mm.
Methods: Sixty-seven children treated surgically at our hospital from March 2016 to September 2021 for lateral condylar fracture of the humerus with displacement > 2 mm were retrospectively analyzed. The children were divided into two groups where early surgery consisted of patients being operated on within 24-h post-injury (n = 36) and delayed surgery consisted of children operated after 24-h post-injury (n = 31).
Background: The purpose of this study was to evaluate the safety and efficacy of vancomycin-loaded calcium sulfate beads and negative-pressure wound therapy (NPWT) in treating children with acute hematogenous osteomyelitis (AHOM).
Methods: A retrospective cohort study was conducted from January 2017 to January 2020 examining children (n = 60) with AHOM who were treated with surgical debridement followed by vancomycin-loaded calcium sulfate beads and NPWT (n = 32) and compared to treatment by conventional surgical debridement (n = 28) followed by NPWT. Conventional surgical treatment consisted of fenestration of necrotic infected bone, debridement of surrounding soft tissue, and washing of the medullary canal before the application of NPWT.
Increasing cases of carbapenem-resistant (CR-KP) infections have been observed globally where multi-drug resistance to CR-KP can make the infection difficult to treat. In recent years, the β-lactam/β-lactamase inhibitor, ceftazidime-avibactam (CAZ-AVI), has been developed to treat complicated urinary tract infections and complicated intra-abdominal infections. CAZ-AVI is approved for children over 3-month old but has yet to be investigated for cases of osteomyelitis.
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- Ossotide is shown to effectively promote the differentiation of osteoblasts, which are cells crucial for bone formation.
- The study indicates that ossotide may enhance the expression of miR-145, a microRNA that is notably reduced in patients with osteogenesis imperfecta (OI).
- The results demonstrate that increasing miR-145 levels led to elevated expression of osteoblast differentiation markers such as Runx2 and Osx, along with activation of Wnt signaling pathways.
The effect of mechanical stretch stress on the differentiation and apoptosis of human growth plate chondrocytes.
In Vitro Cell Dev Biol Anim
February 2017
The study is aimed to investigate the effect of stretch stress with different intensities on the differentiation and apoptosis of human plate chondrocytes. In the present study, the human epiphyseal plate chondrocytes were isolated and cultured in vitro. Toluidine blue staining and type II collagen immunohistochemical staining were used to identify the chondrocytes.
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