Publications by authors named "Zeineb Chemkhi"
Comparison of Fixed and Live Cell-Based Assay for the Detection of AChR and MuSK Antibodies in Myasthenia Gravis.
Neurol Neuroimmunol Neuroinflamm
January 2023
Article Synopsis
- A study compared fixed and live cell-based assays (CBAs) to detect acetylcholine receptors (AChRs) and muscle-specific tyrosine kinase (MuSK) antibodies in myasthenia gravis patients and controls, focusing on those who tested negative for antibodies via radioimmunoassay (RIA).
- Live CBAs detected antibodies in a higher proportion of RIA-dSN samples compared to fixed CBAs (18.6% vs. 11.6%), revealing new cases missed by fixed CBAs.
- Both assays showed high sensitivity for RIA-positive samples, with fixed CBA at 98.5% and live CBA at 100% for AChR Abs, and both