Publications by authors named "Zeinab Tamtaji"
Lung cancer is the most fatal cancer worldwide. The etiology of lung cancer has yet to be fully characterized. Smoking and air pollution are several risk factors for lung cancer.
View Article and Find Full Text PDFCan infliximab serve as a new therapy for neuropsychiatric symptoms?
Naunyn Schmiedebergs Arch Pharmacol
September 2024
Article Synopsis
- * Tumor necrosis factor alpha (TNFα) is an inflammatory substance that plays a role in these disorders, making its inhibition a relevant target for treatment.
- * Infliximab, a medication used for inflammatory conditions, has shown promise in improving issues like cognitive dysfunction, depression, and anxiety, suggesting it could be an effective option for treating neuropsychiatric disorders. *
Article Synopsis
- Neuropsychiatric and neurological disorders are major global health issues, creating a demand for new treatment strategies.
- Fingolimod (FTY720), primarily used for multiple sclerosis, shows potential in treating various neurological conditions by influencing processes like apoptosis, oxidative stress, and neuroinflammation.
- It helps boost memory and synaptic function by altering glutamate and GABA levels in the brain, suggesting it could be a broad-spectrum neuroprotective agent warranting further research.
Gastrointestinal cancer is the most fatal cancer worldwide. The etiology of gastrointestinal cancer has yet to be fully characterized. Alcohol consumption, obesity, tobacco, Helicobacter pylori and gastrointestinal disorders, including gastroesophageal reflux disease, gastric ulcer, colon polyps and non-alcoholic fatty liver disease are among the several risks factors for gastrointestinal cancers.
View Article and Find Full Text PDFClearance of accumulated protein aggregates is one of the functions of autophagy. Recently, a clearer understanding of non-coding RNAs (ncRNAs) functions documented that ncRNAs have important roles in several biological processes associated with the development and progression of neurodegenerative disorders. Subtypes of ncRNA, including microRNA (miRNA), long noncoding RNA (lncRNA), and circular RNA (circRNA), are commonly dysregulated in neurodegenerative disorders such as Alzheimer and Parkinson diseases.
View Article and Find Full Text PDFNeurological disorders are a major group of non-communicable diseases affecting quality of life. Non-Coding RNAs (ncRNAs) have an important role in the etiology of neurological disorders. In studies on the genesis of neurological diseases, aquaporin 4 (AQP4) expression and activity have both been linked to ncRNAs.
View Article and Find Full Text PDFLong non-coding RNAs (lncRNAs) can be utilized as prognostic indicators of gastric cancer since they can affect several cancer-related processes. Coumarin is a natural product with some useful anti-cancer properties. Here, we measured the expression of selected lncRNAs (RuPAR, SNHG6, CASC11, and their targets, miR-340-5p, p21, E-cadherin, and CDK1) in AGS gastric cancer cells treated with coumarin.
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