Non-rigid registration of Fluorescein Angiography and Optical Coherence Tomography via scanning laser ophthalmoscope imaging.

Fluorescein Angiography (FA) imaging is the gold standard technique for neurovascular imaging regarding assessing neurovascular diseases such as Diabetic Retinopathy (DR) and Diabetic Macular Edema (DME). On the other hand, as FA imaging is invasive and does not provide any depth information, Optical Coherence Tomography (OCT) imaging technique is a good complementary for it in diagnosis process. To correlate the information of both FA and OCT images, an image alignment/registration process is needed.

Automatic detection of Hyperreflective Foci in optical coherence tomography B-scans using Morphological Component Analysis.

Hyperreflective Foci (HF) is one of the most common complications distributed in cross-sectional images of patients with Diabetic Macular Edema (DME). Scanning Laser Ophthalmoscope (SLO) images usually consists of several B-scans that represent a cross-sectional reconstruction of a plane through the anterior or posterior regions of retina. In each B-scan, HFs are geometrically distinct constituents in different retinal layers.