Thymoquinone reduces mouse colon tumor cell invasion and inhibits tumor growth in murine colon cancer models.

We have shown that thymoquinone (TQ) is a potent antitumor agent in human colorectal cancer cells. In this study, we evaluated TQ's therapeutic potential in two different mice colon cancer models [1,2-dimethyl hydrazine (DMH) and xenografts]. We also examined TQ effects on the growth of C26 mouse colorectal carcinoma spheroids and assessed tumor invasion in vitro.

Nitrogen and carbon dynamics of a foliar biotrophic fungal parasite in fertilized Douglas-fir.

•  We investigated the nutritional dynamics of Phaeocryptopus gaeumannii and the impact of nitrogen (N) fertilization of Douglas-fir (Pseudotsuga menziesii) on the production of P. gaeumannii fungal fruiting bodies. Emergence of P.