Publications by authors named "Zehra Dhanani"

Article Synopsis
  • Interstitial lung disease (ILD) includes a variety of lung diseases marked by inflammation and fibrosis, often leading patients to require hospitalization and possibly ICU care due to respiratory failure.
  • Diagnosis of ILD relies heavily on chest CT scans, while acute exacerbations necessitate thorough evaluation for triggers and possible infections, with treatments like corticosteroids, oxygen therapy, and careful ventilation strategies.
  • Advanced treatments like lung transplantation may be considered for those with end-stage ILD, but the decision hinges on the patient's condition and urgency of the situation.
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Article Synopsis
  • Fever in the ICU often isn't due to infections, as seen in a case where a young man had high fevers and lung issues unresponsive to antibiotics.
  • Examination findings pointed to hemophagocytic lymphohistiocytosis (HLH) with significant complications like liver and spleen enlargement, high triglycerides, anemia, and low platelets.
  • Early recognition of HLH is crucial due to its high mortality risk and the potential for it to mimic other conditions, such as ARDS, complicating diagnosis in critical care.
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Purpose Of Review: This review delves into the intricate landscape of airway complications post lung transplantation. With the rising prevalence of end-stage lung disease and the increasing number of lung transplantation worldwide, understanding and effectively managing airway complications are crucial. Given the nuanced nature of these complications and the array of treatment options available, this review aims to provide a comprehensive overview of how to identify, classify, mitigate risk factors for, and manage these complications.

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Background: The Rotterdam Score (RS) on CT head is a new evolving clinical tool as a predictor of mortality in Traumatic Brain Injury (TBI). The objective of this study is to assess the outcome of children with TBI admitted in paediatric intensive care unit (PICU) of a tertiary-care, university hospital by using RS.

Methods: This was a prospective observational study conducted on children (age: 1mo -16yr) with TBI admitted in PICU of Aga Khan University Hospital from 2013 to 2016.

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Background: Transfusion-Related Acute Lung Injury (TRALI) is a major cause of transfusionrelated morbidity and mortality in the intensive care unit setting. There is a paucity of such data from Pakistan. The purpose of this study is to assess the incidence and outcome of TRALI in critically ill children admitted in a pediatric intensive care unit (PICU) of Pakistan.

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