Publications by authors named "Zehra Cengisiz"
Article Synopsis
- The study investigates the role of miRNA and cytokines in tuberculosis (TB), focusing on their potential as biomarkers for distinguishing between healthy individuals and TB patients, as well as their association with treatment response and bacterial genotypes.
- It includes 200 participants, divided into active TB, latent TB, and healthy controls, to analyze miRNA and cytokine expression levels at different stages of the disease.
- Results indicate a significant decrease in specific miRNAs and cytokines in pulmonary TB patients compared to healthy controls, but no significant relationship was found between the clinical course of the disease, cytokine and miRNA expression, and the bacterial genotypes.
Background/aim: Although cutting edge procedures such as cell-free fetal DNA isolation from maternal blood are now available, invasive prenatal tests are still being used extensively for prenatal diagnosis. The study aims to evaluate the demographic data, indications, and cytogenetic results of 9297 results of patients who underwent prenatal invasive testing for genetic analysis that were referred for the last 20 years in a University Medical Genetics Center.
Materials And Methods: The records of 8363 amniocenteses, 626 chorionic villus, and 308 cordocenteses samples were retrospectively evaluated and analyzed regarding referral reasons, indications and their cytogenetic results.