Publications by authors named "Zehou Fang"
The phosphatase inhibitor BVT-948 can be used to efficiently screen functional sexual development proteins in the malaria parasite Plasmodium berghei.
Int J Parasitol Drugs Drug Resist
December 2024
Article Synopsis
- The study focuses on understanding the molecular mechanisms behind Plasmodium sexual development to aid in malaria eradication efforts through the use of phosphatase inhibitors.
- Researchers investigated how a specific phosphatase inhibitor, BVT-948, impacted protein phosphorylation in Plasmodium gametocytes, leading to insights on their development.
- Findings revealed that seven proteins affect sexual development in Plasmodium berghei, indicating that phosphatase inhibitors can be effective tools for identifying essential proteins in the lifecycle of malaria parasites.