Accuracy analysis of the new artificial anatomical marker positioning method (shoulder-to-shoulder) in preventing leg length discrepancy in total hip arthroplasty.

Objective: By comparing the hip arthroplasty parameters planned with the AIHIP three-dimensional simulation surgery system, this study analyzes the accuracy of the new femoral-side "shoulder-to-shoulder" artificial anatomical marker positioning method in femoral-side prosthesis implantation and the prevention of leg length discrepancy in hip arthroplasty.

Methods: A retrospective collection of 47 patients who underwent initial total hip arthroplasty at our hospital from August 2020 to December 2022 and met the inclusion and exclusion criteria was used as the study subjects. The average age was 67.

Cellular functions and biomedical applications of circular RNAs.

Circular RNAs (circRNAs) have emerged as a large class of stable and conserved RNAs that are derived primarily from back-splicing of pre-mRNAs and expressed in a cell- and tissue-specific fashion. Recent studies have indicated that a subset of circRNAs may undergo translation through cap-independent pathways mediated by internal ribosome entry sites (IRESs), m6A modifications, or IRES-like short elements. Considering the stability and low immunogenicity of circRNAs, transcribed circRNAs hold great promise in biomedical applications.

Ultrawide Bandgap Diamond/ε-GaO Heterojunction pn Diodes with Breakdown Voltages over 3 kV.

Robust bipolar devices based on exclusively ultrawide bandgap (UWBG) semiconductors are highly desired for advanced power electronics. The heterojunction strategy has been a prevailing method for fabricating a bipolar device due to the lack of effective bipolar doping in the same UWBG material. Here, we demonstrate a unique heterojunction design integrating the p-type diamond and n-type ε-GaO that achieves remarkable breakdown voltages surpassing 3000 V.

Long COVID symptoms 6 months after acute infection among people living with HIV and people not living with HIV.

Background: Chronic viral infections, such as Human Immunodeficiency Virus (HIV), and their reactivation are considered potential contributing factors to Long-Corona Virus Disease (LC). However, research on the long-term sequelae of Long-COVID in individuals with HIV is limited.

Methods: We conducted a case-control study involving a total of 84 participants categorized into two groups: people living with HIV (PLWH) and people not living with HIV (PNLWH) within the six-month post-infection LC population.

Research on high beam quality 3 × 1 double-cone fiber signal combiner at 9 kW level.

The fiber signal combiner with high output power and high beam quality is an urgent problem to be solved. In this paper, the structure of the double-cone (both the input fibers and the output fiber are tapered) is proposed to improve the beam quality of the fiber signal combiner, and it is verified by simulation and experiment, with the output fiber of 50 µm core tapered to 35 µm as an example. The prepared 3 × 1 double-cone fiber signal combiner reaches the output power of 8.

Super broadband light source: a promising master oscillator source for high brightness and high-power fiber amplifiers.

Stimulated Raman scattering (SRS) and transverse mode instability (TMI) effects are crucial limitation factors for further power scaling of high-power fiber amplifiers with near-diffraction-limited beam quality. It is an important research direction to carry out laser system optimization from the perspective of seed construction. In this work, we experimentally investigated the impact of utilizing different seed lasers on the SRS and TMI characteristics in high power ytterbium-doped fiber amplifiers.

Kinematic differences between female national and provincial athletes in the tennis serve.

Background: Tennis, the second-largest ball game in the world, has a particularly wide audience. To date, little research has been conducted on the biomechanics of female serves.

Purpose: The purpose of this study was to capture the key moments by using 1,000 frames/s high-speed video analysis, to analyze the kinematics of the serving techniques of national athletes and provincial athletes, to determine the differences between the two levels of athletes, and to provide theoretical references for the improvement of scientific training level.

Lactylation in cancer: Mechanisms in tumour biology and therapeutic potentials.

Lactylation, a recently identified form of protein post-translational modification (PTM), has emerged as a key player in cancer biology. The Warburg effect, a hallmark of tumour metabolism, underscores the significance of lactylation in cancer progression. By regulating gene transcription and protein function, lactylation facilitates metabolic reprogramming, enabling tumours to adapt to nutrient limitations and sustain rapid growth.

Room-Temperature Synthesis of a Fluorine-Functionalized Nanoporous Organic Polymer for Highly Efficient SF Adsorption and Separation.

Sulfur hexafluoride (SF) is widely used in the power industry and significantly contributes to the greenhouse effect, necessitating the development of efficient materials for SF capture, particularly fluorine-containing materials. However, existing fluorine-containing materials often require complex monomers and high synthesis temperatures. Herein, we report the synthesis of a fluorine-functionalized carbazole-based nanoporous organic polymer (CNOP-7) at room temperature, using commercially available 4,4'-bis(9-carbazole-9-yl)-1,1'-biphenyl and 1,1,1-trifluoroacetone.

Deep learning application in prediction of cancer molecular alterations based on pathological images: a bibliographic analysis via CiteSpace.

Background: The advancements in artificial intelligence (AI) technology for image recognition were propelling molecular pathology research into a new era.

Objective: To summarize the hot spots and research trends in the field of molecular pathology image recognition.

Methods: Relevant articles from January 1st, 2010, to August 25th, 2023, were retrieved from the Web of Science Core Collection.

4.8-μm CO-filled hollow-core silica fiber light source.

Mid-infrared (MIR) fiber lasers are important for a wide range of applications in sensing, spectroscopy, imaging, defense, and security. Some progress has been made in the research of MIR fiber lasers based on soft glass fibers, however, the emission range of rare-earth ions and the robustness of the host materials are still a major challenge for MIR fiber lasers. The large number of gases provide a variety of optical transitions in the MIR band.

Escherichia coli on colorectal cancer: A two-edged sword.

Escherichia coli (E. coli) is a ubiquitous symbiotic bacterium in the gut, and the diversity of E. coli genes determines the diversity of its functions.

Engineering Nanoporous Polyaminal Networks for Superior SO Capture and Selectivity.

Designing adsorbent materials with high SO adsorption capacities and selectivity remains a significant challenge in flue gas desulfurization. This work focuses on developing two nitrogen-rich nanoporous polyaminal networks (NPANs), which demonstrate promising capabilities for SO adsorption and separation. Two nitrogen-rich nanoporous polyaminal networks, NPAN-5 and NPAN-6, were synthesized via a one-pot method using thiophene-2,5-dicarbaldehyde and furan-2,5-dicarbaldehyde with 1,4-bis(2,4-diamino-1,3,5-triazine)-benzene, respectively.

Room-temperature synthesis of a fluorine-functionalized nanoporous organic polymer for efficient SF separation.

Addressing the environmental impact of SF, we synthesized a fluorine-functionalized triphenylamine-based nanoporous organic polymer, ANOP-8, at room temperature using ,,','-tetraphenylbenzidine and 2,3,4,5,6-pentafluorobenzaldehyde. ANOP-8, which incorporates 14.86% fluorine, has a BET surface area of 694 m g and a robust C-C structure.

Waterborne polyurethane with curcumin moieties for rapid responsive warnings and emergency antimicrobial action: Application in crab freshness preservation.

The ideal smart food-packaging film exhibits responsive color warnings and antimicrobial properties when food metamorphism starts. However, in practical applications, these film responses are slow, usually taking several days, which is not conducive to effective antimicrobial effects. In this study, natural plant-derived curcumin was introduced into waterborne polyurethane (WPU) dispersions through two modes: free-state and end-capping.

Metabolic labeling based methylome profiling enables functional dissection of histidine methylation in C3H1 zinc fingers.

Protein methylation is a functionally important post-translational modification that occurs on diverse amino acid residues. The current proteomics approaches are inefficient to discover the methylation on residues other than Arg and Lys, which hinders the deep understanding of the functional role of rare protein methylation. Herein, we present a methyl-specific metabolic labeling approach for global methylome mapping, which enable the acquisition of methylome dataset covering diverse methylation types.

HO-Activatable Liposomal Nanobomb Capable of Generating Hypoxia-Irrelevant Alkyl Radicals by Photo-Triggered Cascade Reaction for High-Performance Elimination of Biofilm Bacteria.

High HO levels are widely present at the infection sites or in the biofilm microenvironment. Herein, hemin with peroxidase-like catalytic activity and its substrate, 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), are simultaneously introduced into a liposomal nanoparticle containing thermosensitive 2,2'-azobis[2-(2-imidazolin-2-yl) propane] dihydrochloride (AIBI)-loaded bovine serum albumin (BAG), rationally constructing an HO-activatable liposomal nanobomb (Lipo@BHA) for combating biofilm-associated bacterial infections with high performance. In the presence of HO, hemin can catalyze the conversion of ABTS into its oxidized form (ABTS·) with strong near-infrared (NIR) absorption, which produces photonic hyperpyrexia to cause the decomposition of AIBI into oxygen-independent alkyl radicals (·R) and nitrogen (N) microbubbles.

Gender-specific prognosis models reveal differences in subarachnoid hemorrhage patients between sexes.

Background: Subarachnoid hemorrhage (SAH) represents a severe stroke subtype. Our study aims to develop gender-specific prognostic prediction models derived from distinct prognostic factors observed among different-gender patients.

Methods: Inclusion comprised SAH-diagnosed patients from January 2014 to March 2016 in our institution.

Highly Selective SO Capture by Triazine-Functionalized Triphenylamine-Based Nanoporous Organic Polymers.

The emissions of sulfur dioxide (SO) from combustion exhaust gases pose significant risks to public health and the environment due to their harmful effects. Therefore, the development of highly efficient adsorbent polymers capable of capturing SO with high capacity and selectivity has emerged as a critical challenge in recent years. However, existing polymers often exhibit poor SO/CO and SO/N selectivity.