Comprehensively Optimizing Fenton Reaction Factors for Antitumor Chemodynamic Therapy by Charge-Reversal Theranostics.

Chemodynamic therapy (CDT) is a highly tumor-specific treatment, while its efficacy is compromised by the intratumoral Fenton reaction efficiency, which is determined by the following reaction factors, including the availability of Fenton ions (e.g., Fe), the amount of HO, and the degree of acidity.

Zinc oxide spiky nanoparticles: A promising nanomaterial for killing tumor cells.

Zinc oxide (ZnO) nanostructures have been widely studied in biomedical fields due to their special properties. In recent years, ZnO spherical nanoparticles (SNPs) with nano-size as an anti-tumor agent have been widely concerned. While the effects of the non-spherical shaped ZnO nanoparticles on tumor cell death have been rarely reported.

The effects of surface topography of nanostructure arrays on cell adhesion.

Nanostructure arrays have drawn much attention and are promising as new biomaterials in the field of biomedicine. In recent years, numerous experimental studies on the cell behavior of nanostructured arrays (NSs) have been published, describing a wide variety of experimental results. But there are only a few theoretical analyses that elucidate the mechanisms of interactions between cells and nanostructures.