Multi-scale coupling between LFP and EMG in mice by low- intensity pulsed ultrasound stimulation with different number of tone-burst.

Low-intensity pulsed ultrasound stimulation (LIPUS) as a non-invasive, high-spatial resolution and high penetration depth brain modulation technology has been used for modulating neuromuscular function. However, the modulation of neural electrical signal changes in the neuromuscular system by LIPUS remains to be explored. In this study, we stimulated the mouse brain motor cortex by LIPUS with different number of tone burst (NTB) and recorded the local field potential (LFP) signals of the target region and electromyography (EMG) of tail muscle.