Allicin induces cell cycle arrest and apoptosis of breast cancer cells in vitro via modulating the p53 pathway.

Background: The tumor suppressor protein p53 is a most promising target for the development of anticancer drugs. Allicin (diallylthiosulfinate) is one of the most active components of garlic (Alliium sativum L.) and possesses a variety of health-promoting properties with pharmacological applications.