A co-produced mixed methods protocol: Exploring perceptions of oral health care and quality of life in people with mental health conditions.

This planned mixed methods protocol is designed to explore oral health care for individuals living with serious mental health conditions (SMHC). It was co-produced by academics, people with lived experience of mental health conditions, and oral and mental health clinicians. The study seeks to explore oral health quality of life predictors and oral health care experiences of people diagnosed with serious mental health conditions (e.

A case study on experiences with integrated technologies in a care home for older adults.

To facilitate independent living for the growing population of older adults, innovative housing solutions such as novel concepts of care homes with integrated technologies have been developed. This case study exposes a significant gap between the intended goal of fostering independence in older adults and the actual impact of technology on their daily lives. The study explored perceptions, experiences, and needs regarding residents' use of integrated technologies along with the technologies' contribution to handling their everyday life in a Care+ home.

Solvent concentration at 50% protein unfolding may reform enzyme stability ranking and process window identification.

As water miscible organic co-solvents are often required for enzyme reactions to improve e.g., the solubility of the substrate in the aqueous medium, an enzyme is required which displays high stability in the presence of this co-solvent.

Physician Assistant Student Attitudes About People With Serious Mental Illness.

Introduction: This study explored the attitudes of physician assistant (PA) students toward the future care of individuals with serious mental illness (SMI). Physician assistant student education offers a unique opportunity to confront and reduce bias toward individuals with SMI. However, no previous literature has documented PA student attitudes toward SMI.

Experienced barriers in the use of ICT for social interaction in older adults ageing in place: a qualitative systematic review protocol (SYSR-D-22-00848).

Background: Several information and communication technologies (ICT) have been developed to enhance social connectedness of older adults aging in place, although they are not accessible for all. Barriers in using ICT might for example relate to health issues, sensory loss, lack of technical skills, or reluctance to use technologies. Though knowledge on these barriers is crucial for the development and implementation of ICT for older adults, no systematic review was found on this subject.

and Evaluation of ABCG2 (BCRP) Inhibitors Derived from Ko143.

Breast cancer resistance protein (BCRP, ABCG2) is an efflux transporter that plays a crucial role in multidrug resistance to antineoplastic drugs. Ko143, an analogue of the natural product fumitremorgin C, is a potent inhibitor of ABCG2 but is rapidly hydrolyzed to an inactive metabolite . To identify ABCG2 inhibitors with improved metabolic stability, we have assessed a series of Ko143 analogues for their ability to inhibit ABCG2-mediated transport in -transduced MDCK II cells and determined the stability of the most potent compounds in liver microsomes.

Visiomode: An open-source platform for building rodent touchscreen-based behavioral assays.

Background: Touchscreen-based behavioral assays provide a robust method for assessing cognitive behavior in rodents, offering great flexibility and translational potential. The development of touchscreen assays presents a significant programming and mechanical engineering challenge, where commercial solutions can be prohibitively expensive and open-source solutions are underdeveloped, with limited adaptability.

New Method: Here, we present Visiomode (www.

Physical therapy students' perceptions for working with persons with mental illness in the USA.

Background: Physical therapists provide important services for improving health and function for the general population; however, physical therapy (PT) is infrequently accessed by persons with a primary diagnosis of severe mental illness (SMI). This study examined the attitudes of PT students before and during their participation in a service-learning (SL) program for people with SMI.

Materials And Methods: A cross-sectional institutional review board approved qualitative study collected 1-h semi-structured qualitative interviews from seven graduates of a doctor of PT program.

Dental pre-doctoral student perceptions about serious mental illness: Concerns and role clarification.

Purpose/objectives: Little is understood about dental student perspectives providing care to people with serious mental illness (SMI), a population with significant oral health disparities. This study explored student perceptions, questions and beliefs about people with SMI using the Social Ecological Model as a framework to better understand perspectives and identify potential educational needs in dental medicine curricula for providing care to this population.

Methods: Survey data was collected in spring of 2021 from predoctoral dental students (n = 126) enrolled in a required course at a mid-Atlantic university.

eHealth Platforms to Promote Autonomous Life and Active Aging: A Scoping Review.

New technologies, namely eHealth platforms, are being used more than ever before. These platforms enable older people to have a more independent lifestyle, enhance their participation, and improve their well-being. Information and communication technologies are expected to be linked to the triad of aging, social inclusion, and active participation, which is in line with the implementation of Smart Healthy and Age-Friendly Environments.

Bridging religion and spirituality with gestalt psychotherapy to improve clinical symptoms: Preliminary findings using gestalt pastoral care.

An inherent tension between religion and psychotherapy has inhibited the conversation between the two paradigms in determining the most effective approaches to improving mental health outcomes for people of faith. Preliminary research has suggested that the intersection between the two may prove fruitful in providing mental health interventions. As a part of a broader big-data study sponsored by the Bridges Consortium of Brigham Young University and underwritten by the John Templeton Foundation, the present study evaluated the effectiveness of the spiritually integrated strategies of the modality Gestalt Pastoral Care (GPC) focusing on two goals: (a) determining the overall clinical effectiveness of GPC, not previously scientifically validated, and (b) evaluating the effectiveness of GPC in the reduction of symptoms most commonly seen in clients using empirically validated clinical measures.

Multidimensional wellness for people aging with mental health conditions: A proposed framework.

Objective: This project aimed to develop a synthesized framework of multidimensional wellness for people aging with serious mental health conditions (SMHC) using existing frameworks to serve as a guide for policy and interventions to address the unique needs, experiences, and strengths of the population.

Method: A concept analysis compared a widely used wellness approach (Swarbrick, 1997) for people with SMHC and one for older adults (Fullen, 2019) to synthesize into a practical framework for people aging with SMHC.

Results: Nine dimensions were proposed for conceptualizing the wellness of this population including: (a) Developmental, (b) Intellectual/Cognitive, (c) Physical, (d) Emotional, (e) Social, (f) Occupational, (g) Spiritual, (h) Environmental, and (i) Financial.

Old before their time: Comparisons of people with SMI and healthy older adults.

Objective: Compare physical functional measures of people with severe mental illness (SMI) to standardized geriatric values.

Method: Retrospective analysis of physical functioning sample data of middle-aged people with SMI was compared to standardized older adult data. Compared: Sit to Stand Test (STS; = 68), 6 min Walk Test (6MWT; = 71), and Single Legged Stance Test (SLS; = 55).

Service learning experiences of doctor of physical therapy students with a severe mental illness population.

Introduction: Physical therapists provide important services to improve physical health for the general population; however, physical therapy interventions are less utilized with underserved populations such as those with severe mental illness (SMI). The quality of services for these populations is impacted in part by negative provider attitudes and lack of preparation to work with the SMI population. This study examined the impact of structured educational field experience on the physical therapist's attitudes and knowledge about working with the SMI population.

Dynamic data-driven meta-analysis for prioritisation of host genes implicated in COVID-19.

The increasing body of literature describing the role of host factors in COVID-19 pathogenesis demonstrates the need to combine diverse, multi-omic data to evaluate and substantiate the most robust evidence and inform development of therapies. Here we present a dynamic ranking of host genes implicated in human betacoronavirus infection (SARS-CoV-2, SARS-CoV, MERS-CoV, seasonal coronaviruses). We conducted an extensive systematic review of experiments identifying potential host factors.

Genetic mechanisms of critical illness in COVID-19.

Host-mediated lung inflammation is present, and drives mortality, in the critical illness caused by coronavirus disease 2019 (COVID-19). Host genetic variants associated with critical illness may identify mechanistic targets for therapeutic development. Here we report the results of the GenOMICC (Genetics Of Mortality In Critical Care) genome-wide association study in 2,244 critically ill patients with COVID-19 from 208 UK intensive care units.

Challenges Experienced by Behavioral Health Organizations in New York Resulting from COVID-19: A Qualitative Analysis.

This paper presents a qualitative content analysis of survey data collected from behavioral health care providers from throughout New York regarding the challenges faced as a result of COVID-19. Survey responses from 295 agency and program administrators and staff, representing 238 organizations, were analyzed. Ten themes were identified: business operations, service provision, telehealth, safety, client concerns, staff concerns, supplies, technology, illness/grief/loss, and communication.

Care2Caregivers: A Retrospective Examination of Needs Addressed and Services Provided by a Peer Support Helpline.

Family caregivers of persons with Alzheimer's disease and related dementias (CADRD) provide significant support to their family members but often experience challenges and stress that impact their quality of life. Peer supporters can be an important resource to help alleviate stress associated with caregiving, yet few published studies have examined peer supporters for CADRD. This retrospective cohort study examined data collected from a peer support helpline for CADRD in a middle Atlantic state.

Accelerometer Triad Calibration for Pole Tilt Compensation Using Variance Based Sensitivity Analysis.

In Engineering Geodesy, most coordinate frames are aligned with the local vertical. For many measurement tasks, it is therefore necessary to manually (or arithmetically) align sensors or equipment with the local vertical, which is a common source of errors and it is very time consuming. Alternatively, accelerometer triads as part of inertial measurement units (IMUs) are used in several applications for horizon leveling.

Faculty Mentorship in Allied Health Schools: A Program Evaluation of a Mentorship Initiative.

Mentorship is an important career development resource for junior faculty and one that may be particularly important for those who begin their career as allied health clinicians before transitioning to academia. To support junior faculty at an allied health school, a formal mentoring program was established within a rehabilitation and counseling department. The program was started in response to a school-wide effort to promote faculty development and increase scholarly productivity.

Tools for Moving On: Adapting an Evidence-Based Housing Curriculum for Individuals Receiving Services in an Inpatient Psychiatric Setting to Prepare for Community Living.

Individuals with serious mental illness transitioning from state psychiatric hospitals to community living need specialized skills to enter community housing programs. There are few examples of best practice hospital group programs to improve community living skills. To address this gap, the authors developed a community skills training and discharge readiness program, Tools for Moving On (TFMO), adapted from materials from the Substance Abuse and Mental Health Services Administration Permanent Supportive Housing: Tools for Tenants toolkit.