Prediction of clinical efficacy of acupuncture intervention on upper limb dysfunction after ischemic stroke based on machine learning: a study driven by DSA diagnostic reports data.

Objective: To develop a machine learning-based model for predicting the clinical efficacy of acupuncture intervention in patients with upper limb dysfunction following ischemic stroke, and to assess its potential role in guiding clinical practice.

Methods: Data from 1,375 ischemic stroke patients with upper limb dysfunction were collected from two hospitals, including medical records and Digital Subtraction Angiography (DSA) reports. All patients received standardized acupuncture treatment.

Janus Doping of Sulfur into Platinum Diselenide Ribbons.

2D platinum diselenide (PtSe), a novel member of the transition metal dichalcogenides (TMDCs) family, possesses many excellent properties, including a layer-dependent bandgap, high carrier mobility, and broadband response, making it promise for applications in technologies like field-effect transistors and room-temperature photodetectors. Doping represents an effective method to modify the electrical properties of 2D TMDCs and to bestow upon them additional functions. However, to date, little research has been conducted on the successful doping of 2D PtSe for modification.

Machine-Learning-Assisted Development of Gel Polymer Electrolytes for Protecting Zn Metal Anodes from the Corrosion of Water Molecules.

Rechargeable aqueous zinc-ion batteries (RAZIBs) offer low cost, high energy density, and safety but struggle with anode corrosion and dendrite formation. Gel polymer electrolytes (GPEs) with both high mechanical properties and excellent electrochemical properties are a powerful tool to aid the practical application of RAZIBs. In this work, guided by a machine learning (ML) model constructed based on experimental data, polyacrylamide (PAM) with a highly entangled structure was chosen to prepare GPEs for obtaining high-performance RAZIBs.

Size-Dependent Uptake and Depuration of Nanoplastics in Tilapia () and Distinct Intestinal Impacts.

Nanoplastics (NPs, <1 μm) are of great concern worldwide because of their high potential risk toward organisms in aquatic systems, while very little work has been focused on their tissue-specific toxicokinetics due to the limitations of NP quantification for such a purpose. In this study, NPs with two different sizes (86 and 185 nm) were doped with palladium (Pd) to accurately determine the uptake and depuration kinetics in various tissues (intestine, stomach, liver, gill, and muscle) of tilapia () in water, and subsequently, the corresponding toxic effects in the intestine were explored. Our results revealed uptake and depuration constants of 2.

Small-Molecule Acceptor with Unsymmetric Substituents and Fused Rings for High-Performance Organic Solar Cells with Enhanced Mobility and Reduced Energy Losses.

A new unsymmetric small-molecule acceptor (SMA) BTPOSe-4F was designed by unsymmetric structure modification to Y6 with an alkyl upper side chain replaced by an alkoxy side chain and a sulfur atom in its central fused ring replaced by a selenium atom, for the application as an acceptor to fabricate organic solar cells (OSCs). BTPOSe-4F exhibits a higher lowest unoccupied molecular orbital (LUMO) energy level, a reduced nonradiation energy loss, and better charge extraction properties in its binary OSCs with a higher of 0.886.

Protein Corona-Mediated Extraction for Quantitative Analysis of Nanoplastics in Environmental Waters by Pyrolysis Gas Chromatography/Mass Spectrometry.

There is a growing concern about the effects of nanoplastics on biological safety and human health because of their global ubiquity in the environment. Methodologies for quantitative analysis of nanoplastics are important for the critical evaluation of their possible risks. Herein, a sensitive yet simple and environmentally friendly extraction approach mediated by protein corona is developed and coupled to pyrolysis-gas chromatography/mass spectrometry (Py-GC/MS) for nanoplastic determination in environmental waters.

Quantitative Analysis of Polystyrene and Poly(methyl methacrylate) Nanoplastics in Tissues of Aquatic Animals.

Micro- and nanoplastics unavoidably enter into organisms and humans as a result of widespread exposures through drinking waters, foods, and even inhalation. However, owing to the limited availability of quantitative analytical methods, the effect of nanoplastics inside animal bodies is poorly understood. Herein, we report a sensitive and robust method to determine the chemical composition, mass concentration, and size distribution of nanoplastics in biological matrices.

Recent progress in two-dimensional materials for terahertz protection.

With the wide applications of terahertz (THz) devices in future communication technology, THz protection materials are essential to overcome potential threats. Recently, THz metamaterials (MMs) based on two-dimensional (2D) materials (, graphene, MXenes) have been extensively investigated due to their unique THz response properties. In this review, THz protection theories are briefly presented first, including reflection loss and shielding mechanisms.

Research of insomnia on traditional Chinese medicine diagnosis and treatment based on machine learning.

Background: Insomnia as one of the dominant diseases of traditional Chinese medicine (TCM) has been extensively studied in recent years. To explore the novel approaches of research on TCM diagnosis and treatment, this paper presents a strategy for the research of insomnia based on machine learning.

Methods: First of all, 654 insomnia cases have been collected from an experienced doctor of TCM as sample data.

Ultrastable radical-doped coordination compounds with antimicrobial activity against antibiotic-resistant bacteria.

In the present work, we have introduced a series of stable radical-doped coordination compounds composed of donor-acceptor structures and shown to produce organic radicals in situ as a result of unconventional lone pair-π interactions in ambient conditions. Inconspicuous lone pair-π and C-Hπ interactions were shown to play a key role in self-assembly as well as the charge transfer process, resulting in a long-lived charge-separated state able to generate organic radicals. The resultant species displayed broad-spectrum antimicrobial activity, including against multi-drug-resistant bacteria.

Application of a Coupling Agent to Improve the Dielectric Properties of Polymer-Based Nanocomposites.

In this work, an easy, low-cost, and widely applicable method was developed to improve the compatibility between the ceramic fillers and the polymer matrix by adding 3-aminopropyltriethoxysilane (KH550) as a coupling agent during the fabrication process of BaTiO3-P(VDF-CTFE) nanocomposites through solution casting. Results show that the use of KH550 can modify the surface of ceramic nanofillers; therefore, good wettability on the ceramic-polymer interface was achieved, and the enhanced energy storage performances were obtained by a suitable amount of the coupling agent. This method can be used to prepare flexible composites, which is highly desirable for the production of high-performance film capacitors.

Strategy of Residual Stress Determination on Selective Laser Melted Al Alloy Using XRD.

Selective laser melting (SLM) is known to generate large and anisotropic residual stresses in the samples. Accurate measurement of residual stresses on SLM-produced samples is essential for understanding the residual stress build-up mechanism during SLM, while a dramatic fluctuation can be observed in the residual stress values reported in the literature. On the basis of studying the influence of surface roughness on residual stress measured using X-ray diffraction (XRD), we propose a procedure coupling XRD technique with pretreatment consisting of mechanical polishing and chemical etching.

Transparent Electrothermal Film Defoggers and Antiicing Coatings based on Wrinkled Graphene.

Fog, frost, ice, and other natural phenomena can inevitably affect human life and the function of equipment. Therefore, removal or prevention is an urgent problem to be solved. As a new type of 2D material, graphene possesses great application potential in defogging and antiicing.

Multiresponsive Tetradentate Phosphorescent Metal Complexes as Highly Sensitive and Robust Luminescent Oxygen Sensors: Pd(II) Versus Pt(II) and 1,2,3-Triazolyl Versus 1,2,4-Triazolyl.

Two Pd(II) complexes based on tetradentate chelate ligands with either a 1,2,4-triazolyl (Pd1) or 1,2,3-triazolyl (Pd2) unit were synthesized, and their structure-property relationships were studied. Both Pd1 and Pd2 are rare bright deep blue Pd(II) phosphors with contrasting properties. Pd1 displays stimuli-responsive luminescence in response to UV irradiation, concentration, or temperature change, which is ascribed to the facile switching of monomer to excimer emission.

Rescuing ocular development in an anophthalmic pig by blastocyst complementation.

Porcine-derived xenogeneic sources for transplantation are a promising alternative strategy for providing organs for treatment of end-stage organ failure in human patients because of the shortage of human donor organs. The recently developed blastocyst or pluripotent stem cell (PSC) complementation strategy opens a new route for regenerating allogenic organs in miniature pigs. Since the eye is a complicated organ with highly specialized constituent tissues derived from different primordial cell lineages, the development of an intact eye from allogenic cells is a challenging task.

Formation of Uniform Water Microdroplets on Wrinkled Graphene for Ultrafast Humidity Sensing.

Portable humidity sensors with ultrafast responses fabricated in wearable devices have promising application prospects in disease diagnostics, health status monitoring, and personal healthcare data collecting. However, prolonged exposures to high-humidity environments usually cause device degradation or failure due to excessive water adsorbed on the sensor surface. In the present work, a graphene film based humidity sensor with a hydrophobic surface and uniformly distributed ring-like wrinkles is designed and fabricated that exhibits excellent performance in breath sensing.