Publications by authors named "Ze-feng Gao"
Objective: Previous works have outlined the pivotal involvement of long intergenic non-coding RNA (lincRNA) in cancer progression, while the efficiency of LINC01234 in pancreatic cancer remained obscure. The purpose of this research is to unravel the regulatory mechanism of LINC01234 in pancreatic cancer via modulating microRNA (miR)-513a-3p and hexose 6-phosphate dehydrogenase (H6PD).
Methods: Pancreatic cancer cells were cultured and clinical tissue specimens were collected.
[Study on the birth order of patients with esophagus cancer in Shanxi province].
Zhonghua Liu Xing Bing Xue Za Zhi
November 2012
Objective: To explore the relationship between esophagus cancer patients and both environmental and genetic factors, through analyzing the data on birth orders from esophagus cancer patients of Shanxi province.
Methods: Both Greenwood and Haldane methods on birth order were used to study the 1101 cases with esophagus cancer from Shanxi province. All the patients had received surgery and were diagnosed, by pathological evidence.
[Studies on the risks of cardia neoplasm among immediate relatives of the patients in Shanxi province].
Zhonghua Liu Xing Bing Xue Za Zhi
November 2012
Objective: To analyze the different risks of cardia neoplasms in the immediate relatives of the cardia cancer patients, through a case-control study.
Methods: A case-control study was adopted on 772 cases and 772 controls, and relative risk (RR) were measured to compare the results from paternal or matrilineal groups.
Results: (1) Risk of the 1st grade kinship to the male cardia-cancer-patient group was obviously higher than that of the control group with RR = 2.
Article Synopsis
- The study investigates the link between the XRCC1 Arg399Gln gene polymorphism and the risk of hepatocellular carcinoma (liver cancer) in the Chinese Han population.
- A meta-analysis was conducted including 6 studies with a total of 1,246 patients and 1,953 controls, revealing a significant association between the gene variant and increased cancer risk.
- The findings suggest that individuals with the XRCC1 Arg399Gln polymorphism face a higher risk of developing hepatocellular carcinoma, particularly noted in specific genetic comparisons.