Publications by authors named "Ze-Yun Zhu"
Eur J Med Chem
December 2021
Article Synopsis
- Parkinson's disease (PD) is a common neurodegenerative disorder, and early diagnosis is crucial yet challenging.
- Researchers have created new compounds called styrylaniline derivatives that can bind to alpha-synuclein (α-syn) aggregates, which are linked to PD.
- One particular compound, 7-16, not only effectively detects these aggregates in cells and mouse models but also can cross the blood-brain barrier, indicating its potential for use in imaging agents for PD diagnosis.
