Effects of driving pressure-guided ventilation on postoperative pulmonary complications in patients with COVID-19 undergoing abdominal surgery: A post-hoc propensity score-matched analysis.

Background: Application of individualized positive end-expiratory pressure (PEEP) based on minimum driving pressure facilitates to prevent from postoperative pulmonary complications (PPCs). Whether lung protective ventilation strategy can reduce the risk of PPCs in COVID-19 patients remains unclear. In this study, we compared the effects of driving pressure-guided ventilation with conventional mechanical ventilation on PPCs in patients with COVID-19.

[Protective effect of ulinastatin on lung injury induced by simultaneous pancreas-kidney transplantation in piglet].

Objective: To evaluate the effects of ulinastatin (UTI) on lung injury induced by simultaneous pancreas-kidney transplantation in piglet.

Methods: With reproduction of simultaneous pancreas-kidney transplantation model in piglets, 12 couples of piglets were randomly divided into two groups (n=12). Piglets in UTI group were given a constant infusion of UTI 15 kU x kg(-1) x h(-1) by means of a pump during operation.