Publications by authors named "Ze-Ming Zhou"
Fibromuscular dysplasia (FMD) is a non-atherosclerotic, non-inflammatory vascular disease involving small-to-medium-sized arteries. The characteristics of Chinese patients with FMD remain unclear. We retrospectively analyzed the data of patients with renal FMD who underwent percutaneous transluminal renal angioplasty (PTRA) for the first time at Fuwai Hospital between 2010 and 2021.
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- Apparent mineralocorticoid excess (AME) is a genetic condition that leads to low-renin hypertension, low aldosterone levels, and high cortisol to cortisone metabolite ratios due to mutations in the HSD11B2 gene.* -
- It affects the enzyme 11β-HSD2, which converts cortisol to cortisone, and has over 50 identified mutations that impair enzyme function through various molecular mechanisms.* -
- Early and accurate diagnosis through genetic testing is crucial for effective management of AME, helping to prevent severe health complications related to target organ damage.*
Background: Liddle syndrome is a form of monogenic hypertension caused by mutations in the three homologous subunits of the epithelial sodium channels (ENaCs), α, β, and γ. It is characterized by early-onset refractory hypertension, hypokalemia, low renin activity, and hypoaldosteronism. In this study, we report a novel frame-shift mutation in responsible for Liddle syndrome in a Chinese family.
View Article and Find Full Text PDFShape statistics variational approach for the outer contour segmentation of left ventricle MR images.
IEEE Trans Inf Technol Biomed
July 2006
Segmentation of left ventricles is one of the important research topics in cardiac magnetic resonance (MR) imaging. The segmentation precision influences the authenticity of ventricular motion reconstruction. In left ventricle MR images, the weak and broken boundary increases the difficulty of segmenting the outer contour precisely.
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