Publications by authors named "Ze-Long Ma"
Article Synopsis
- Extrahepatic cholangiocarcinoma sarcoma is a very rare cancer type that features both epithelial and mesenchymal cells, making it difficult to study due to the lack of available cell lines.
- The primary aim of the research was to create and characterize a new cell line called CBC2T-2, utilizing various methods like STR testing, cloning assays, and tumorigenicity tests in mice to understand its properties and potential for therapeutic research.
- Results confirmed the authenticity of the CBC2T-2 line, revealing unique cellular characteristics including high proliferation, migratory and invasive abilities, and distinct chromosomal structures that can aid in further studies on cholangiocarcinoma sarcoma treatments.
We report the spatiotemporal mode-locked multimode fiber laser operating at 1.55 µm based on semiconductor saturable absorber mirrors with the mode-locking threshold as low as 104 mW. Benefiting from the multimode interference filtering effect introduced in the laser cavity not only the central wavelength can be continuously tuned from 1557 nm to 1567 nm, but also the number of the output pulses can be adjusted from 1 to 4 by simply adjusting the polarization controllers.
View Article and Find Full Text PDFDicer1 is an enzyme essential for microRNA (miRNA) maturation. The loss of miRNAs resulted from Dicer1 deficiency greatly contributes to the progression of many diseases, including lipid dysregulation, but its role in hepatic accumulation of free cholesterol (FC) that is critical in the development of non-alcoholic steatohepatitis (NASH) remains elusive. In this study, we used the liver-specific Dicer1-knockout mice to identify the miRNAs involved in hepatic FC accumulation.
View Article and Find Full Text PDFPrevious studies have shown that microRNA-1304 (miR-1304) is dysregulated in certain types of cancers, including non-small cell lung cancer (NSCLC), and might be involved in tumor survival and/or growth. In this study we investigated the direct target of miR-1304 and its function in NSCLC in vitro. Human lung adenocarcinoma cell lines (A549 and NCI-H1975) were studied.
View Article and Find Full Text PDFObjective: To compare changes of blood clotting state after initial trauma fractures and twice trauma fractures, investigate the effect of fracture history to the state of the blood clotting after secondary trauma fractures.
Methods: Thirty New Zealand rabbits were selected, aged 5-6 months, males and females unlimited, weighted 2.4-2.